Tick salivary gland extract-activated transmission of Borrelia afzelii spirochaetes

Title:

Tick salivary gland extract-activated transmission of Borrelia afzelii spirochaetes

Creator:

Pechová, Jitka , Štěpánová, Gabriela, Kovář, Lubomír, and Kopecký, Jan

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:582f4a58-5e03-403d-89f1-3b8dbf61fde9
uuid:582f4a58-5e03-403d-89f1-3b8dbf61fde9
doi:10.14411/fp.2002.027

Subject:

Ixodes ricinus, salivary gland extract, Borrelia afzelii, and transmission

Type:

model:article and TEXT

Format:

bez média and svazek

Description:

Saliva-activated transmission of Borrelia afzelii Canica, Nato, du Merle, Mazie, Baranton et Postic, 1993 was demonstrated using salivary gland extract (SGE) from Ixodes ricinus (L., 1758) ticks and C3H mice. Injection of Borrelia spirochaetes together with SGE increased the level of bacteraemia and accelerated the appearance of bacteria in the urinary bladder, compared with the injection of spirochaetes alone. More I. ricinus nymphs became infected when feeding on mice inoculated with B. afzelii plus SGE. Analysis of cytokines produced by cells of draining lymph nodes from SGE-treated mice showed a suppression of proinflammatory cytokines IFN-γ, IL-6 and GM-CSF following a transient upregulation in comparison with the control mice infected without SGE.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Coverage:

153-159

Source:

Folia parasitologica | 2002 Volume:49 | Number:2

Harvested from:

CDK

Metadata only:

false