Vitamin D3 action within the ovary - an updated review

Title:

Vitamin D3 action within the ovary - an updated review

Creator:

Grzesiak, Małgorzata

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:5a5c85fa-7c3e-4d65-a7da-9b220afef0f6
uuid:5a5c85fa-7c3e-4d65-a7da-9b220afef0f6
doi:10.33549/physiolres.934266

Subject:

vitamin D3, vitamin D3 receptor, ovary, polycystic ovary syndrome, and premature ovarian failure

Type:

model:article and TEXT

Format:

počítač and online zdroj

Description:

Vitamin D3 is well-known as a major regulator of calcium and phosphorus homeostasis. A growing body of evidence highlights its crucial role in the regulation of reproductive processes in females. The role of vitamin D3 in the female reproductive tract has been extensively investigated because its receptor is abundant in reproductive organs, including ovary. Importantly, besides expression of vitamin D3 receptor, the ovary is an extrarenal site of vitamin D3 metabolism. The influence of vitamin D3 on follicular development and ovarian steroidogenesis has been investigated. Furthermore, vitamin D3 deficiency has also been associated with polycystic ovary syndrome, premature ovarian failure and ovarian cancer. The objective of this review is to summarize our knowledge about the contribution of vitamin D3 to physiological and pathological processes within the ovary.

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Coverage:

371-378

Source:

Physiological research | 2020 Volume:69 | Number:3

Harvested from:

CDK

Metadata only:

false