N-methyl-D-aspartate prevented memory deficits induced by MK-801 in mice

Title:

N-methyl-D-aspartate prevented memory deficits induced by MK-801 in mice

Creator:

Zdeněk Hliňák and Ivan Krejčí

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:6236de77-138f-4f3a-8b0d-b78def71812a
uuid:6236de77-138f-4f3a-8b0d-b78def71812a
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, fyziologie, myši, physiology, mice, N-methyl-D-aspartate, MK-801, spatial memory, elevated plus-maze, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

An interaction between N-methyl-D-aspartate (NMDA) and MK-801 was examined in mice using a modified elevated plus-maze paradigm that allows assessment of the adaptive form of spatial memory. NMDA administered (s.c.) immediately after the acquisition session protected the animals against the amnesia induced by MK-801 given shortly before the retention session. Behavioral performance, expressed as the transfer latency, and therefore spatial memory potency of NMDA plus MK-801 treated animals was comparable with that of both NMDA-treated animals and the controls., Z. Hliňák, I. Krejčí., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2003 Volume:52 | Number:6

Harvested from:

CDK

Metadata only:

false