Vegetable oils used as vitamin E vehicle affect the electrical activity of rat heart

Title:

Vegetable oils used as vitamin E vehicle affect the electrical activity of rat heart

Creator:

Ozdemir, S., Ayaz, M., Tuncer, T., Ugur, M., and Turan, B.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:64e7db95-6180-4f58-b0b2-58f60eaada43
uuid:64e7db95-6180-4f58-b0b2-58f60eaada43
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, vitamin E, fyziologie, physiology, action potential, corn oil, penaut oil, hazelnut oil, papillary muscle, atrial muscle, repolarization, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

The aim of this study is to define the possible effects of vegetable oils used as vitamin E vehicle on the electrical activity of the rat heart. To test the possible effects of vitamin E vehicles we studied the effect of i.p. injected corn oil, hazelnut oil or peanut oil on the action potential parameters recorded in both papillary and left atrial muscle strips. Four experimental groups were used. The control group was injected (i.p.) with distilled water, while the three remaining groups received injections of corn oil, hazelnut oil, or peanut oil for five weeks (in a dose of 0.4 ml/kg/day - minimum amount of oil in which vitamin E could be dissolved). We used borosilicated (15-20 MΩ) capillary electrodes and intracellular action potentials (AP) were recorded in isolated papillary and left atrium muscle strips. While administration of three different types of vegetable oil had no significant effect on AP parameters of papillary muscle, they significantly prolonged the repolarization phase of AP in atrial strips. These results show that vegetable oils used as vitamin E vehicles may alter the electrical activity of the heart in a tissue-dependent manner. The present data indicate that the possible effect of vegetable oil vehicles should be kept in mind while evaluating the possible effects of in vivo vitamin E administration., S. Ozdemir, M. Ayaz, T. Tuncer, M. Ugur, B. Turan., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2003 Volume:52 | Number:6

Harvested from:

CDK

Metadata only:

false