Biochemical Changes of Enzymatic Defense System after Phenanthrene Exposure in Olive Flounder, Paralichthys olivaceus

Title:

Biochemical Changes of Enzymatic Defense System after Phenanthrene Exposure in Olive Flounder, Paralichthys olivaceus

Creator:

Jee, J.-H and Kang, J.-C

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:692864c4-628a-4d88-a98a-86cb7bcd9f5d
uuid:692864c4-628a-4d88-a98a-86cb7bcd9f5d

Subject:

Antioxidant enzymes, Detoxification, Oliver flounder, Phase II enzyme, and Phenanthrene

Type:

article, model:article, and TEXT

Description:

The objective of this study was to investigate the early biological response in the olive flounder exposed to sub-lethal concentrations of waterborne phenanthrene (0.5, 1 or 2 μM). The fish were exposed for 4 weeks and we analyzed their enzymatic defense system, antioxidant and phase II enzyme activities, to evaluate the chronic exposure toxicity of phenanthrene. Waterborne phenanthrene affected antioxidant enzymes and glutathione-mediated detoxification as an enzyme defense system. Hepatic, gill and kidney glutathione reductase as well as glutathione S-transferase, and catalase activities were markedly elevated after two or four weeks of exposure. These enzyme activities of the olive flounder, Paralichthys olivaceus, seem to be a convenient approach for monitoring pollution in coastal areas against polycyclic aromatic hydrocarbon pollution including phenanthrene.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2005 Volume:54 | Number:6

Harvested from:

CDK

Metadata only:

false