Enteral nutrition and hepatosplanchnic region in critically ill patients - friends or foes?

Title:

Enteral nutrition and hepatosplanchnic region in critically ill patients - friends or foes?

Creator:

Richard Rokyta, Martin Matějovič, Aleš Kroužecký, and Novák, I.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:6aa4dd04-b767-455f-ab7e-b5e330afca6b
uuid:6aa4dd04-b767-455f-ab7e-b5e330afca6b
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, sepse, sepsis, enteral nutrition, hepatosplanchnic region, critically ill, nonocclusive bowel necrosis, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Enteral nutrition (EN) is a preferred way of feeding in critically ill patients unless obvious contraindications such as ileus or active gastrointestinal bleeding are present. Early enteral nutrition as compared to delayed EN or total parenteral nutrition decreases morbidity in postsurgical and trauma patients. The hepatosplanchnic region plays a pivotal role in the pathophysiology of sepsis and multiple organ dysfunction syndrome. The beneficial effects of EN on splanchnic perfusion and energy metabolism have been documented both in healthy volunteers and animal models of sepsis, hemorrhagic shock and burns. By contrast, EN may increase splanchnic metabolic demands, which in turn may lead to oxygen and/or energy demand/supply mismatch, especially when hyperemic response to EN is not preserved. Therefore, the timing of initiation and the dose of EN in patients with circulatory failure requiring vasoactive drugs are a matter of controversy. Interestingly, the results of recent clinical studies suggest that early enteral nutrition may not be harmful even in patients with circulatory compromise. Nevertheless, possible onset of serious complications, the non-occlusive bowel necrosis in particular, have to be kept in mind. Unfortunately, there is only a limited number of clinically applicable monitoring tools for the effects of enteral nutrition in critically ill patients., R. Rokyta Jr., M. Matějovič, A. Kroužecký, I. Novák., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2003 Volume:52 | Number:1

Harvested from:

CDK

Metadata only:

false