Effect of acute alcohol treatment on dopamine concentration in corpus striatum of rats: a voltammetric study

Title:

Effect of acute alcohol treatment on dopamine concentration in corpus striatum of rats: a voltammetric study

Creator:

Diaz, N. and Murgaš, K.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:6ea11039-770d-4f93-a468-0a337b9d839c
uuid:6ea11039-770d-4f93-a468-0a337b9d839c

Subject:

rats, alcohol treatment, dopamine in striatum, and voltammetric determination

Type:

article, model:article, and TEXT

Description:

A voltammetry technique has been used to determine changes in dopamine release in the rat corpus striatum after two doses of ethanol administration. The dopamine oxidation current reached a maximal value at 30 min after the first alcohol dose with a subsequent decrease towards the initial level at 60 min and kept to the basal level with a statistically insignificant oscillation. When a second dose of alcohol was applied at 60 min, it was followed by a decrease of the dopamine oxidation current peak to 50 % of the initial value after another 60 min observation. The results resemble the known effect of alcohol on human behaviour (excitation followed by depression).

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 1992 Volume:41 | Number:2

Harvested from:

CDK

Metadata only:

false