Insulin-Like Growth Factor Binding Protein-3 in Patients with Liver Cirrhosis

Title:

Insulin-Like Growth Factor Binding Protein-3 in Patients with Liver Cirrhosis

Creator:

Kateřina Kotrčová, Martina Pechová, Karel Kotaška, and Průša, P.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:884a6551-6c25-4ad8-bd54-1e39229aaba2
uuid:884a6551-6c25-4ad8-bd54-1e39229aaba2
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, fyziologie člověka, human physiology, Liver cirrhosis, GFBP-3, Liver tests, 14, and 612

Type:

article, studie, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Aim of the study was to evaluate serum levels of insulin-like growth factor binding protein-3 in patients with liver cirrhosis and to compare serum IGFBP-3 levels with other liver function tests. Fifty-one patients with liver cirrhosis were selected for our study. We measured IGFBP-3 (1.67±1.06 mg/l, mean ± SD), albumin (32±8 g/l), prealbumin (0.22±0.14 g/l), AST (2.29±2.38 mkat/l), ALT (2.11±4.83 mkat/l) and cholinesterase (mean 78.6±45.2 mkat/l) in the serum. There was a significant positive correlation of serum IGFBP-3 with serum albumin and serum cholinesterase. The correlation coefficient was much lower between serum IGFBP-3 and serum prealbumin. There was no significant correlation between serum AST, ALT and IGFBP-3. Serum IGFBP-3 proves to be a better marker for the hepatic synthetic capacity than serum albumin or cholinesterase., K. Šídlová, M. Pechová, K. Kotaška, R. Průša., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2002 Volume:51 | Number:6

Harvested from:

CDK

Metadata only:

false