Correlation of carnitine levels to methionine and lysine intake

Title:

Correlation of carnitine levels to methionine and lysine intake

Creator:

Marica Krajčovičová-Kudláčková, Šimončič, R., Béderová, A., Katarína Babinská, and Igor Béder

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:8907c7af-bb50-4ff6-b627-f18c02e126db
uuid:8907c7af-bb50-4ff6-b627-f18c02e126db
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, karnitin, carnitine, vegans, lactoovovegetarians, omnivores, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Plasma carnitine levels were measured in two alternative nutrition groups - strict vegetarians (vegans) and lactoovovegetarians (vegetarians consuming limited amounts of animal products such as milk products and eggs). The results were compared to an average sample of probands on mixed nutrition (omnivores). Carnitine levels were correlated with the intake of essential amino acids, methionine and lysine (as substrates of its endogenous synthesis), since the intake of carnitine in food is negligible in the alternative nutrition groups (the highest carnitine content is in meat, lower is in milk products, while fruit, cereals and vegetables contain low or no carnitine at all). An average carnitine level in vegans was significantly reduced with hypocarnitinemia present in 52.9 % of probands. Similarly, the intake of methionine and lysine was significantly lower in this group due to the exclusive consumption of plant proteins with reduced content of these amino acids. Carnitine level in lactoovovegetarians was also significantly reduced, but the incidence of values below 30 m mol/l was lower than in vegans representing 17.8 % vs. 3.3 % in omnivores. Intake of methionine and lysine was also significantly reduced in this group, but still higher compared to vegans (73 % of protein intake covered by plant proteins). Significant positive correlation of carnitine levels with methionine and lysine intake in alternative nutrition groups indicates that a significant portion of carnitine requirement is covered by endogenous synthesis. Approximately two thirds of carnitine requirement in omnivores comes from exogenous sources. The results demonstrate the risks of alternative nutrition with respect to the intake of essential amino acids, methionine and lysine, and with respect to the intake and biosynthesis of carnitine., M. Krajčovičová-Kudláčková, R. Šimončič, A. Béderová, K. Babinská, I. Béder., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2000 Volume:49 | Number:3

Harvested from:

CDK

Metadata only:

false