ECG body surface mapping changes in type 1 diabetic patients with and without autonomic neuropathy

Title:

ECG body surface mapping changes in type 1 diabetic patients with and without autonomic neuropathy

Creator:

Sabina Pálová, Szabo, K., Jiří Charvát, Jaroslav Slavíček, Eva Medová, Mikuláš Mlček, and Otomar Kittnar

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:8beda118-709e-4035-97e2-19ef5ad5a405
uuid:8beda118-709e-4035-97e2-19ef5ad5a405

Subject:

Fyziologie člověka a srovnávací fyziologie, diabetes mellitus, diabetes mellitus type 1, autonomic neuropathy, ECG body surface mapping, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print

Description:

ECG body surface mapping (BSM) parameters in patients with diabetes mellitus Type 1 (DM1) are significantly different comparing to healthy non-diabetic subjects. Hypothesis that these changes are more pronounced in DM1 patients with autonomic neuropathy (AN) was tested. The parameters of BSM were registered by diagnostic system Cardiag 112.2 in 54 DM1 patients including 25 with AN and 30 control subjects. AN was diagnosed according to Ewing criteria when two or more Ewing tests were abnormal. In classic 12-lead ECG the heart rate was increased, QRS and QT shortened (p<0.01) and QTC prolonged in DM1 patients. The VCG measurement of QRS-STT angles and spatial QRS-STT angle showed non-significant differences. The absolute values of maximum and minimum in depolarization and repolarization isopotential, isointegral, isoarea maps were significantly different in DM1 patients in comparison with controls (p<0.01). The changes were more pronounced in DM1 patients with AN than in DM patients without AN (p<0.05). The QT duration measured in 82 leads of thorax was significantly shortened in 68 leads of both groups of DM 1 patients (p<0.01) when compared with controls. In 34 of them this shortening was more pronounced in DM1 patients with AN than in DM1 patients without AN (p<0.05). The results showed that the method of ECG BSM is capable to confirm the presence of autonomic neuropathy in diabetic patients., S. Palová ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2010 Volume:59 | Number:2

Harvested from:

CDK

Metadata only:

false