Scanning electron microscopic study of the human uterine tube epithelial lining: surgical biopsy samples and epithelial cell culture

Title:

Scanning electron microscopic study of the human uterine tube epithelial lining: surgical biopsy samples and epithelial cell culture

Creator:

Gálfiová, Paulína, Polák, Štefan, Mikušová, Renáta, Juríková, Miroslava, Klein, Martin, Csöbönyeiová, Mária, Danišovič, Ľuboš, and Varga, Ivan

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:8ff013f8-f718-4cc7-81ab-c3ef41fc4618
uuid:8ff013f8-f718-4cc7-81ab-c3ef41fc4618
doi:10.33549/physiolres.935031

Subject:

uterine/fallopian tube epithelium, ultrastructure, scanning electron microscopy, and fallopian tube epithelial cell in vitro culture

Type:

model:article and TEXT

Format:

počítač and online zdroj

Description:

This article summarizes the importance of the exact morphology of human uterine/fallopian tube epithelium at the scanning electron microscopy (SEM) level for the clinical outcome even nowadays. Visual referential micrographs from SEM reflect two ways to view human epithelial cell lining surfaces: the surface epithelial uterine tube from surgical tissue biopsy and human fallopian tube epithelial cells (HFTEC) culture monolayer surface. One colorized image visualizes ciliated cells, distinguishes them from non-ciliated cells, and provides an educational benefit. A detailed description of the ultrastructure in referential and pathologic human uterine tube epithelium is important in defining the morphological basis of high-grade carcinomas, in the mechanism of pathophysiology, and in discussing options for its prevention. Cell cultures of human fallopian tube epithelial cells offer new approaches in simulating the mechanisms of cancer genesis or may help to elucidate the genetic basis of several diagnoses. New technical approaches in SEM provide higher resolution and detailed surface images. The SEM modality is still one of the current options in diagnostics and may be useful for advancing human reproductive organ cancer research.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Coverage:

S137-S143

Source:

Physiological research | 2022 Volume:71 | Number:Supplement 1

Harvested from:

CDK

Metadata only:

false