Cell-penetrating peptides: a useful tool for the delivery of various cargoes into cells

Title:

Cell-penetrating peptides: a useful tool for the delivery of various cargoes into cells

Creator:

Böhmová, E, Drahomíra Machová, Michal Pechar, Pola, R, Květoslava Venclíková, Olga Janoušková, and Tomáš Etrych

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:9baf0e6e-e58b-4001-8712-5de468e9ab2d
uuid:9baf0e6e-e58b-4001-8712-5de468e9ab2d
issn:0862-8408

Subject:

peptidy, buňky, peptids, cells, cell-penetrating peptides, cell penetration, drug delivery, 14, and 612

Type:

model:article and TEXT

Format:

print, bez média, and svazek

Description:

Cell-penetrating compounds are substances that enhance the cellular uptake of various molecular cargoes that do not easily cross the cellular membrane. The majority of cell-penetrating compounds described in the literature are cell-penetrating peptides (CPPs). This review summarizes the various structural types of cell-penetrating compounds, with the main focus on CPPs. The authors present a brief overview of the history of CPPs, discuss the various types of conjugation of CPPs to biologically active cargoes intended for cell internalization, examine the cell-entry mechanisms of CPPs, and report on the applications of CPPs in research and in preclinical and clinical studies., E. Böhmová, D. Machová, M. Pechar, R. Pola, K. Venclíková, O. Janoušková, T. Etrych., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2018 Volume:67 | Number:Suppl 2

Harvested from:

CDK

Metadata only:

false