Optimal oxygen saturation in extremely premature neonates

Title:

Optimal oxygen saturation in extremely premature neonates

Creator:

Zoban, P. Zoban

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:a1b3876f-c381-4f59-895b-5a47b26bf4e3
uuid:a1b3876f-c381-4f59-895b-5a47b26bf4e3
doi:10.33549/physiolres.933987

Subject:

Prematurity, Extremely premature neonate, Oxygen therapy, Oxygen saturation, and Target range of SpO2

Type:

model:article and TEXT

Format:

bez média and svazek

Description:

So far, great efforts have been made to understand the demands of extremely premature neonates (EPNs´; born before the 28th week of gestation) on postnatal care, including optimal oxygen saturation, that will allow them to survive without disability. A major yet unresolved problem is to find an “optimal range” of their oxygen saturation and to maintain it without drops or increases, i.e., without hypoxia or hyperoxia. The individual sections of this paper deal with the changes of SpO2 (an estimate of SaO2 measured by pulse oximetry) that occur before, during, and after premature labor, postnatal factors affecting SpO2, and especially how to find an acceptable compromise in choosing the most effective and minimally harmful range of SpO2 for EPNs’ with the careful FiO2 adjustment and continually monitored SpO2. At present, the two SpO2 ranges, narrow (90-94 %) vs. wider (88-94 %), are most discussed. However, the question of how much oxygen is too much or little remains unanswered. There is even a view that there is no uniform optimal SpO2 range for EPNs, and that each newborn has its own, individually specific range that changes due to its intrinsic and/or extrinsic factors.

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Coverage:

171-178

Source:

Physiological research | 2019 Volume:68 | Number:2

Harvested from:

CDK

Metadata only:

false