Dominant nucleolus in the progenitor cell using human bone marrow erythroid and granulocytic cell lineages as a model. A morphological and cytochemical note

Title:

Dominant nucleolus in the progenitor cell using human bone marrow erythroid and granulocytic cell lineages as a model. A morphological and cytochemical note

Creator:

Smetana, K., Klamová, H., and Mikulenková, D.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:bbeb56c0-a892-413e-be6e-4c2d8e09fc56
uuid:bbeb56c0-a892-413e-be6e-4c2d8e09fc56

Subject:

dominant nucleoli and progenitor cells

Type:

model:article and TEXT

Format:

bez média and svazek

Description:

Progenitor cells of the human erythroid and granulocytic cell lineages are characterized by the presence of several nucleoli. One of these nucleoli is larger and possesses more fibrillar centres than others. Such nucleolus is apparently dominant in respect of both size and main nucleolar function such as nucleolar-ribosomal RNA transcription. Such nucleolus is also visible in specimens using conventional visualization procedures, in contrast to smaller nucleoli. In the terminal differentiation nucleated stages of the erythroid and granulocytic development, dominant nucleoli apparently disappeared, since these cells mostly contained very small nucleoli of a similar size with one fibrillar centre. Thus, the easily visible dominant nucleoli appear to be useful markers of the progenitor cell state, such as proliferation, and differentiation potential.

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Coverage:

111-115

Source:

Folia biologica | 2020 Volume:66 | Number:3

Harvested from:

CDK

Metadata only:

false