Hypovitaminosis D in children with type 1 diabetes mellitus and its influence on biochemical and densitometric parameters

Title:

Hypovitaminosis D in children with type 1 diabetes mellitus and its influence on biochemical and densitometric parameters
Hypovitaminosis D in children with type 1 diabetes mellitus and its influence on biochemical and densitometric parameters

Creator:

Vojtková, J., Čiljaková, Miriam, Vojarová, L., Janíková, K., Michnová, Z., and Šagiová, Veronika

Contributor:

Vojtková, J., Čiljaková, Miriam, Vojarová, L., Janíková, K., Michnová, Z., and Šagiová, Veronika

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:bmc12017012-5435ab4e-d150-4942-976f-dc1a0c095a24
uuid:bmc12017012-5435ab4e-d150-4942-976f-dc1a0c095a24
local:bmc12017012
http://www.lfhk.cuni.cz/Data/files/Casopisy/2012/2012_18.pdf
local: bmc12017012

Subject:

mladiství, kostní denzita, vápník--metabolismus, dítě, diabetes mellitus 1. typu--komplikace--metabolismus, diabetické nefropatie--komplikace--metabolismus, ženské pohlaví, hemoglobin A glykosylovaný--analýza, lidé, mužské pohlaví, fosfor--metabolismus, nedostatek vitaminu D--komplikace--metabolismus, and mladý dospělý

Type:

model:article, article, Text, statistics, práce podpořená grantem, and TEXT

Format:

braille, electronic resource, remote, and elektronický zdroj

Description:

The aim of the study was to establish the frequency of hypovitaminosis D in children with type 1 diabetes mellitus (T1D), its influence on biochemical and densitometric parameters and the relation to diabetic nephropathy. 58 children with T1D at the age 9–19 years were enrolled to the study. Vitamin D concentration less than 30 ng/ml was considered as insufficient. 37 children (63.79%) had vitamin D level under 30 ng/ml, from these 19 subjects (32.7%) had vitamin D level under 20 ng/ml and 2 subjects (3.44%) under 10 ng/ml. Children with vitamin D deficiency had significantly lower magnesium concentration and lower Z score of lumbar spine (−1.34 ± 1.24 vs. −0.30 ± 1.21, p = 0.01) compared to diabetics with sufficient vitamin D concentration. No significant difference was found in parameters calcium, phosphorus or glycosylated hemoglobin. Patients with diabetic nephropathy (n = 18) showed no significant difference in vitamin D, glycosylated hemoglobin or Z score of lumbar spine compared to the patients without nephropathy (n = 40). Subjects with nephropathy had significantly longer diabetes duration, significantly higher cholesterol and triacylglycerol concentration. In our cohort of patients nearly two thirds of children had insufficient vitamin D concentration what supports the need to monitor and eventually supplement vitamin D in T1D subjects., Jarmila Vojtková, Miriam Čiljaková, Lenka Vojarová, Katarína Janíková, Zuzana Michnová, Veronika Šagiová, and Literatura 35

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Relation:

Acta medica (Hradec Králové)--MED00010947

Source:

Acta medica (Hradec Králové) | 2012 Volume:55 | Number:1

Harvested from:

CDK

Metadata only:

false

Date:

2012