Protective function of ceruloplasmin and its action on erythrocytes in men with prostate tumors

Title:

Protective function of ceruloplasmin and its action on erythrocytes in men with prostate tumors
Protective function of ceruloplasmin and its action on erythrocytes in men with prostate tumors

Creator:

Kotrikadze, N., Zibzibadze, M., Ramishvili, L., Alibegashvili., M., Chigogidze, T., and Managadze, L.

Contributor:

Kotrikadze, N., Zibzibadze, M., Ramishvili, L., Alibegashvili., M., Chigogidze, T., and Managadze, L.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:bmc14045959-f39b4e7a-6631-4bd7-b297-ff02bf6cf412
uuid:bmc14045959-f39b4e7a-6631-4bd7-b297-ff02bf6cf412
local:bmc14045959
http://ojs.journals.cz/index.php/EMHPJ/issue/archive
local: bmc14045959

Subject:

nádory prostaty--farmakoterapie, ceruloplasmin--farmakologie, erytrocyty--účinky léků, biochemická analýza krve, statistika jako téma, staří, lidé, mužské pohlaví, and lidé středního věku

Type:

model:article, article, Text, statistics, and TEXT

Format:

braille, electronic resource, remote, and elektronický zdroj

Description:

Purpose: To investigate the protective action of Ceruloplasmin (Cp) on the lysis of erythrocytes in men with prostate tumors. Material and Methods: The blood erythrocytes of the patients with benign hyperplasia of prostate (BHP) and prostate adenocarcinoma (CaP) were studied. Patients at the age 60-75 with early stages of a cancer have been investigated. The control group was consisted of apparently healthy males with the compatible age. n=15 for each group. The clinical stage of the disease was diagnosed by means of rectal, histological and echographic examination of the prostate gland. Photometric methods were applied to register lysis dynamics in order to test out the protective action of Cp. Results: The nonspecific protective function of Cp preparation on BHP and CaP erythrocytes as well as on the control group erythrocytes was revealed. CaP erythrocytes have shown more sensitivity to the lysis provocative factor than BHP and the control group erythrocytes, that was presumably attributed to the structural and functional changes of the erythrocytes developed in the presence of malignant tumor., N. Kotrikadze, M. Zibzibadze, L. Ramishvili, M. Alibegashvili., T. Chigogidze, L. Managadze, and Literatura

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Relation:

European medical, health and pharmaceutical journal--MED00177703

Source:

European medical, health and pharmaceutical journal : open access reviewed journal | 2011 Volume:2011 | Number:2

Harvested from:

CDK

Metadata only:

false

Date:

2011