Invasive aspergillosis in intensive care unit patients in Iran

Title:

Invasive aspergillosis in intensive care unit patients in Iran
Invasive aspergillosis in intensive care unit patients in Iran

Creator:

Hedayati, Mohammad T, Khodavaisy, Sadegh, Alialy, Masoud, Omran, Saeed Mahdavi, and Habibi, Mohammad R.

Contributor:

Hedayati, Mohammad T, Khodavaisy, Sadegh, Alialy, Masoud, Omran, Saeed Mahdavi, and Habibi, Mohammad R.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:bmc14059429-31a9823b-a345-4951-9821-9904ff8650cd
uuid:bmc14059429-31a9823b-a345-4951-9821-9904ff8650cd
local:bmc14059429
https://www.lfhk.cuni.cz/Faculty/Publications/Acta-Medica/Archive/2013/
local: bmc14059429

Subject:

mladiství, dospělí, staří, staří nad 80 let, aspergilóza--diagnóza--epidemiologie--mikrobiologie, ženské pohlaví, lidé, péče o pacienty v kritickém stavu, mužské pohlaví, lidé středního věku, prospektivní studie, and mladý dospělý

Type:

model:article, article, Text, časopisecké články, práce podpořená grantem, and TEXT

Format:

print, text, and regular print

Description:

We assessed the intensive care unit (ICU) patients for Invasive aspergillosis (IA) with culture and non-culture based diagnostic methods from Iran. Thirty-six ICU patients with underlying predisposing conditions for IA were enrolled in the study. Sixty eight Bronchoalveolar lavage (BAL) samples were collected by bronchoscope twice a weekly. BAL samples were analyzed by microscopic examination, fungal culture and galactomannan (GM) detection. The Platelia Aspergillus GM EIA was used to quantify GM indices. Samples with a BAL GM index > or = 1 were considered as positive for GM. Patients were classified as having probable or possible IA. Out of 36 suspected patients to IA, 36.1% of cases showed IA which were categorized as: 4 cases of possible IA and 9 of probable IA. 76.2% of BAL samples were positive for GM. From 13 patients with IA, 11 (84.6%) had at least one positive BAL GM index. Of these patients, 9 (81.8%) showed probable IA. The main underlying predisposing conditions were neutropenia (53.8%) and COPD (30.8%). Our study has indicated that COPD must be considered as one of the main predisposing condition for occurrence of aspergillosis in ICU patients. Our data have also revealed that GM detection in BAL samples play a significant role to IA diagnosis. and MT. Hedayati, S. Khodavaisy, M. Alialy, SM. Omran, MR. Habibi

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Coverage:

Írán

Relation:

Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové--MED00010947

Source:

Acta medica (Hradec Králové) | 2013 Volume:56 | Number:2

Harvested from:

CDK

Metadata only:

false

Date:

2013