Intra-scleral parathalamus implant: efficacy and safety in rabbit eyes

Title:

Intra-scleral parathalamus implant: efficacy and safety in rabbit eyes
Intra-scleral parathalamus implant: efficacy and safety in rabbit eyes

Creator:

Detorakis, Efstathios T., Loggaki, Konstantina, Karyotakis, Nikolaos, and Ginis, Harilaos

Contributor:

Detorakis, Efstathios T., Loggaki, Konstantina, Karyotakis, Nikolaos, and Ginis, Harilaos

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:bmc15030954-861d0099-e943-419e-878e-62b55959a33f
uuid:bmc15030954-861d0099-e943-419e-878e-62b55959a33f
local:bmc15030954
http://actamedica.lfhk.cuni.cz/
doi: 10.14712/18059694.2015.80
local: bmc15030954

Subject:

zvířata, modely nemocí na zvířatech, ženské pohlaví, glaukom--chirurgie, nitrooční tlak, protézy a implantáty, králíci, and sklerostomie--metody

Type:

model:article, article, Text, časopisecké články, and TEXT

Format:

print, text, and regular print

Description:

PURPOSE: A variety of anti-glaucomatous shunt designs have been proposed so far. This study evaluates the feasibility of a novel shunt design, the intra-scleral parathalamus implant (IPI), in a rabbit eye model. METHODS: Ten healthy albino rabbits were included. Measurements of the IOP, using TonoPenXL, as well as ocular rigidity (OR) and aqueous outflow facility (AO), using a previously described methodology, were performed in both eyes of each animal. Subsequently, the IPI was implanted at the left eye of all animals whereas the right eye served as control. Measurements of IOP were repeated at weekly intervals for 2 months postoperatively whereas measurements of OR and AO were repeated at the 1st and 2nd postoperative week. RESULTS: The IOP decreased significantly whereas the AO increased significantly postoperatively at the operated eyes. A significant postoperative decrease in OR was also recorded at the operated eyes. Respective differences at the fellow eyes were statistically not significant. Two animals developed postoperative complications and were excluded from follow-up. CONCLUSIONS: Results imply that the implantation of the IPI is feasible in rabbit eyes with significant favorable effects on the IOP, AO and OR. and E. T. Detorakis, K. Loggaki, N. Karyotakis, H. Ginis

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Relation:

Acta medica (Hradec Králové) Universitas Carolina, Facultas Medica Hradec Králové--MED00010947

Source:

Acta medica (Hradec Králové) | 2014 Volume:57 | Number:4

Harvested from:

CDK

Metadata only:

false

Date:

2014