Molecular mechanisms and promising role of dihydromyricetin in cardiovascular diseases

Title:

Molecular mechanisms and promising role of dihydromyricetin in cardiovascular diseases

Creator:

Nie, Hao, Ji, Tianyi, Fu, Yu, Chen, Danyang, Tang, Zhouping, and Zhang, Cuntai

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:cef83f3b-9871-411c-9b94-6a25572f3751
uuid:cef83f3b-9871-411c-9b94-6a25572f3751
doi:10.33549/physiolres.934915

Subject:

dihydromyricetin, cardiovascular disease, atherosclerosis, myocardial infarction, and myocardial hypertrophy

Type:

model:article and TEXT

Format:

počítač and online zdroj

Description:

Vine tea, a Chinese herbal medicine, is widely used in traditional Asian medicine to treat common health problems. Dihydromyricetin (DMY) is the main functional flavonoid compound extracted from vine tea. In recent years, preclinical studies have focused on the potential beneficial effects of dihydromyricetin, including glucose metabolism regulation, lipid metabolism regulation, neuroprotection, and anti-tumor effects. In addition, DMY may play a role in cardiovascular disease by resisting oxidative stress and participating in the regulation of inflammation. This review is the first review that summaries the applications of dihydromyricetin in cardiovascular diseases, including atherosclerosis, myocardial infarction, myocardial hypertrophy, and diabetic cardiomyopathy. We also clarified the underlying mechanisms and signaling pathways involved in the above process. The aim of this review is to provide a better understanding and quick overview for future researches of dihydromyricetin in the field of cardiovascular diseases, and more detailed and robust researches are needed for evaluation and reference.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Coverage:

749-762

Source:

Physiological research | 2022 Volume:71 | Number:6

Harvested from:

CDK

Metadata only:

false