Relation between pituitary-thyroid axis hormones and anthropometric parameters in Czech adult population

Title:

Relation between pituitary-thyroid axis hormones and anthropometric parameters in Czech adult population

Creator:

Marcela Dvořáková, Martin Hill, Jarmila Čeřovská, Zita Pobišová, Radovan Bílek, Petra Hoskovcová, Václav Zamrazil, and Vojtěch Hainer

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:dcda9e70-a2e1-4584-87a0-1029aedc6894
uuid:dcda9e70-a2e1-4584-87a0-1029aedc6894
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, endokrinologie, antropometrie, tělesné složení, endocrinology, anthropometry, body composition, body fat distribution, thyrotropin, free thyroxine, free triiodothyronine, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Although the relationships between thyroid function and anthropometric parameters were studied in patients with thyroid disorders and in morbidly obese subjects, such data in normal healthy population are scarce. In our study, relationships between factors of body composition, fat distribution and age with hormones of the pituitary-thyroid axis were evaluated in a large, randomly selected sample of normal adult Czech population comprising of 1012 men and 1625 women. Our results exhibited weak, but significant relationships between body composition, body fat distribution and the parameters of pituitary-thyroid axis. Some of these associations were gender-specific. As shown by backward stepwise regression model, body fat distribution evaluated by centrality index (subscapular/triceps skinfold ratio) was negatively associated with free triiodothyronine (fT3) serum levels only in women, while a positive correlation of fT3 with BMI was specific for men. BMI was inversely related to free thyroxine (fT4) concentrations in women but not in men. The centrality index (CI) was positively related to TSH levels in both genders. The fT3/fT4 ratio, reflecting deiodinase activity, was inversely related to age and positively related to BMI in both genders, while the highly significant negative correlation between CI and fT3/fT4 ratio was specific for women., M. Dvořáková, M. Hill, J. Čeřovská, Z. Pobišová, R. Bílek, P. Hoskovcová, V. Zamrazil, V. Hainer., and Obsahuje bibliiografii a bibliografické odkazy

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2008 Volume:57 | Number:Suppl 1

Harvested from:

CDK

Metadata only:

false