Circulating Neuroactive C21- and C19-Steroids in Young Men Before and After Ejaculation

Title:

Circulating Neuroactive C21- and C19-Steroids in Young Men Before and After Ejaculation

Creator:

Stárka, L., Hill, M., Havlíková, H., Kancheva, L., and Sobotka, V.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:e24674e7-d8a3-4691-b506-b3b2cbe0be16
uuid:e24674e7-d8a3-4691-b506-b3b2cbe0be16

Subject:

Allopregnanolone, Ejaculation, 17a-hydroxypregnenolone, Neuroactive steroids, and Testosterone

Type:

article, model:article, and TEXT

Description:

Twelve neuroactive and neuroprotective steroids, androgens and androgen precursors i.e. 3a,17b-dihydroxy-5a-androstane, 3a-hydroxy-5a-androstan-17-one, 3a-hydroxy-5b-androstan-17-one, androst-5-ene-3b,17b-diol, 3b,17a-dihydroxy-pregn-5-en-20-one (17a-hydroxy-pregnenolone), 3b-hydroxy-androst-5-en-17-one (dehydroepiandrosterone, DHEA), testosterone, androst-4-ene-3,17-dione (androstenedione), 3a-hydroxy-5a-pregnan-20-one (allopregnanolone), 3b-hydroxy-pregn-5-en-20-one (pregnenolone), 7a-hydroxy-DHEA, and 7b-hydroxy-DHEA were measured using the GC-MS system in young men before and after ejaculation provoked by masturbation. The circulating level of 17a-hydroxypregnenolone increased significantly, whereas the levels of other circulating steroids did not change at all. This fact speaks against the hypothesis that a decrease in the level of neuroactive steroids, e.g. allopregnanolone, may trigger the orgasm-related increase of oxytocin as it was reported by other authors.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2006 Volume:55 | Number:4

Harvested from:

CDK

Metadata only:

false