Noninvasive assessment of local myocardium repolarization changes using high resolution surface ECG mapping

Title:

Noninvasive assessment of local myocardium repolarization changes using high resolution surface ECG mapping

Creator:

Tyšler, M., Peter Kneppo, Turzová, M., Švehlíková, J., Slavomír Karas, Eva Nagyová, Karel Hána, and Slavomíra Filipová

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:ef443046-2f39-4982-ad1f-ec42139e7e68
uuid:ef443046-2f39-4982-ad1f-ec42139e7e68
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, fyziologie, physiology, myocardium repolarization, equivalent dipole model, body surface potential mapping, active ECG electrodes, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

A method using body surface potential maps for assessment of myocardium lesions with changed repolarization is presented and suitable mapping system is introduced. Differences between normal and altered QRST integral maps together with torso volume conductor model were used to determine the equivalent dipole representing the lesion. Performance of the method was studied on simulated data. Changed repolarization was modeled by shortening of myocyte action potentials in regions typical for stenosis of the main coronary arteries. The equivalent dipole estimated the positions of small lesions with a mean error of 9±4 mm (17±14 mm for larger transmural lesions). The subepicardial or subendocardial character of the lesions was reflected in the dipole orientation. Tests of the method on patients after myocardial infarction that underwent coronary intervention on a single coronary vessel showed that in 7 of 8 successfully treated patients the dipole position matched well with the treated vessel. A small dipole moment in another patient indicated unsuccessful treatment. The method was implemented in a new 128-channel mapping system. Its active electrodes, battery powered measuring unit and optical computer interface help to minimize noise in ECG and guarantee patient´s safety. The results suggest that the method and mapping system offer useful tools for noninvasive identification of local repolarization changes in the myocardium., M. Tyšler, P. Kneppo, M. Turzová, J. Švehlíková, S. Karas, E. Hebláková, K. Hána, S. Filipová., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2007 Volume:56 | Number:Suppl 1

Harvested from:

CDK

Metadata only:

false