Hormonal and psychobehavioral predictors of weight loss in response to a short-term weight reduction program in obese women

Title:

Hormonal and psychobehavioral predictors of weight loss in response to a short-term weight reduction program in obese women

Creator:

Vojtěch Hainer, Karolína Hlavatá, Milena Gojová, Marie Kunešová, Martin Wagenknecht, Vojtěch Kopský, Jana Pařízková, Martin Hill, and Jara Nedvídková

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:f6a62a50-86c4-408e-850c-82c077ca3930
uuid:f6a62a50-86c4-408e-850c-82c077ca3930
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, endokrinologie, obezita, hormony, endocrinology, obesity, hormones, weight loss predictors, eating inventory, Beck depression inventory, anthropometric indexes, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Among the factors influencing weight loss and maintenance, psychobehavioral, nutritional, metabolic, hormonal and hereditary predictors play an important role. Psychobehavioral factors influence adherence to lifestyle changes and thus weight loss maintenance. The outcome of short-term weight reduction treatment is mainly affected by changes in energy and nutrient intake and physical activity and thus the impact of hormones can possibly be obscured. In order to reveal hormonal determinants of weight loss, a 4-week in-patient comprehensive weight reduction program was introduced in which food intake and physical activity were under the strict control. Women (n = 67, BMI: 32.4 ± 4.4 kg; age: 48.7 ± 12.2 years) who exhibited stable weight on a 7 MJ/day diet during the first week of weight management were given a hypocaloric diet yielding daily energy deficit 2.5 MJ over the subsequent 3-week period. This treatment resulted in a mean weight lo ss of 3.80 ± 1.64 kg. Correlation analysis revealed that baseline concentrations of several hormones were significantly associated either with a higher (free triiodothyronine, C-peptide, growth hormone, pancreatic polypeptide) or with a lower (insulin-like growth factor-I, cortisol, adiponectin, neuropeptide Y) reduction of anthropometric parameters in response to weight management. In a backward stepwise regression model age, initial BMI together with baseline levels of growth hormone, peptide YY, neuropetide Y and C-reactive protein predicted 49.8 % of the variability in weight loss. Psychobehavioral factors (items of the Eating Inventory, Beck Depression score) did not contribute to weight change induced by a well-controlled short-term weight reduction program., V. Hainer, K. Hlavatá, M. Gojová, M. Kunešová, M. Wagenknecht, V. Kopský, J. Pařízková, M. Hill, J. Nedvídková., and Obsahuje bibliografii a bibliografické údaje

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2008 Volume:57 | Number:Suppl 1

Harvested from:

CDK

Metadata only:

false