Relationship between dynamic expiratory time constant τedyn and parameters of breathing cycle in pressure support ventilation mode

Title:

Relationship between dynamic expiratory time constant τedyn and parameters of breathing cycle in pressure support ventilation mode

Creator:

Čandik, P. , Rybár, D. , Depta, F. , Sabol, F. , Kolesár, A. , Galková, K. , Török, P. , Doničová, V. , Imrecze, Š., Nosáľ, M. , and Donič, V.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:f953f00f-7c8b-468a-befb-89f125a573f4
uuid:f953f00f-7c8b-468a-befb-89f125a573f4

Subject:

time constant, weaning from ventilator, time of breathing cycle •, and breathing cycle

Type:

model:article and TEXT

Format:

bez média and svazek

Description:

Study of the relationship between ventilation parameters: monitored expiratory time constant – τedyn and breathing – trigger frequency (ftrig) and time of breathing cycle (Tcy) are main goals of this article. Parameters were analyzed during last 4±2 h before weaning from ventilation in 66 patients ventilated in pressure support mode (PSV). We have found out, that there exist mathematical relationships, observed during adequate gas exchange, yet not described. Monitored parameters are represented by τedyn, ftrig and Tcy. The analysis showed close negative correlation between Tcy and ftrig (R2 =0.903). This implies that each increasing of τedyn causes decreasing of ftrig and vice versa. The calculation of regression equation between τedyn and Tcy outlined that Tcy = 5.2625 * τedyn + 0.1242 (R2 =0.85). Regulation of respiratory cycles by the respiratory center in the brain is probably based on evaluation of τedyn as the τedyn probably represents a regulatory element and Tcy regulated element. It can be assumed, that respiratory center can optimize the work of breathing in order to minimize energy in system patient + ventilator. The unique relationship, described above could be useful in clinical practice for development of new ventilation modes.

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2018 Volume:67 | Number:6

Harvested from:

CDK

Metadata only:

false