UV Rays, the Prooxidant/Antioxidant Imbalance in the Cornea and Oxidative Eye Damage

Title:

UV Rays, the Prooxidant/Antioxidant Imbalance in the Cornea and Oxidative Eye Damage

Creator:

Čejková, J., Štípek, S., Crkovská, J., Ardan, T., Pláteník, J., Čejka, Č., and Midelfart, A.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:fce3048e-9400-4dea-8902-298614d8c236
uuid:fce3048e-9400-4dea-8902-298614d8c236

Subject:

Cornea, UV rays, and Prooxidant/antioxidant imbalance

Type:

article, model:article, and TEXT

Description:

In this minireview, the factors involved in the development of corneal injury due to an increased amount of UVB rays are summarized. Experimental studies have shown that an increased number of UVB rays leads to a profound decrease in corneal antioxidants (high molecular weight, antioxidant enzymes as well as low molecular weight, mainly ascorbic acid) so that a prooxidant/antioxidant imbalance appears. The decrease of corneal antioxidant protective mechanisms results in oxidative injury of the cornea and causes damage of the inner parts of the eye by UVB rays and by reactive oxygen species generated by them.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2004 Volume:53 | Number:1

Harvested from:

CDK

Metadata only:

false