Resting membrane potential and Na+,K+-ATPase of rat fast and slow muscles during modeling of hypogravity

Title:

Resting membrane potential and Na+,K+-ATPase of rat fast and slow muscles during modeling of hypogravity

Creator:

Tyapkina, O., Volkov, E., Nurullin, L., Shenkman, B., Kozlovskaya, I., Nikolsky, E., and František Vyskočil

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:fdffc1b4-552b-4cbc-9288-e1f52105fe40
uuid:fdffc1b4-552b-4cbc-9288-e1f52105fe40

Subject:

Fyziologie člověka a srovnávací fyziologie, fyziologie, kosterní svaly, human physiology, striated muscles, EDL, soleus, resting membrane potential, hypogravity, sodium pump, 14, and 612

Type:

article, články, model:article, and TEXT

Description:

Antiorthostatic hindlimb suspension (unloading) decreased the resting membrane potential (RMP) of skeletal muscle fibers in fast extensor digitorum longus (EDL) and slow soleus (SOL) muscle of the rat by about 10 % within 7 days and more. Inactivation of the membrane Na+,K+-pump by ouabain brought about similar depolarization as unloading. The increased sodium permeability of the membrane was excluded as the major cause of this depolarization by experiments in which TRIS was substituted for Na+ in the medium. On the other hand, the decrease in the electrogenic participation of the Na+,K+-pump is apparently one of the causes of RMP decrease during hypogravity, in EDL muscle in particular., O. Tyapkina ... [et al.]., and Obsahuje seznam literatury

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2009 Volume:58 | Number:4

Harvested from:

CDK

Metadata only:

false