This paper presents a new robust adaptive model predictive control for a special class of continuous-time non-linear systems with uncertainty. These systems have bounded disturbances with unknown upper bound, as well as constraints on input states. An adaptive control is used in the new controller to estimate the system uncertainty. Also, to avoid the system disturbances, a H∞ method is employed to find the appropriate gain in Tube-MPC. Finally, a surge avoidance problem in centrifugal compressors is solved to show the efficiency and effectiveness of the proposed algorithm.
Tumor necrosis factor a (TNFa) was found to be significantly increased in skeletal muscles and retroperitoneal fat of obese insulin-resistant Koletsky rats as compared to control Wistar rats. This increase was accompanied by a depression of insulin receptor protein tyrosine kinase (PTK) activity. Neither the insulin-binding capacity nor insulin receptor affinity were related to this TNFa increase in these tissues. In the liver, no significant changes of TNFa content and only a lowering of insulin-binding capacity were found. It is concluded that an increased TNFa content in muscles and fat (but not in the liver) contributes to insulin resistance by lowering insulin receptor protein tyrosine kinase activity, while other insulin receptor characteristics (insulin-binding capacity and affinity of insulin receptors to the hormone) do not seem to be influenced by this factor., A. Hřebíček, M. Rypka, Z. Chmela, J. Veselý, M. Kantorová, V. Golda., and Obsahuje bibliografii
Job Scheduling in Computational Grids is gaining importance due to the need for efficient large-scale Grid-enabled applications. Among different optimization techniques designed for the problem, Genetic Algorithm (GA) is a popular class of solution methods. As GAs are high level algorithms, specific algorithms can be designed by choosing the genetic operators as well as the evolutionary strategies such as Steady State GAs and Struggle GAs. In this paper we focus on Struggle GAs and their tuning for scheduling of independent jobs in computational grids. Our results showed that a careful hash implementation for computing the similarity of solutions was able to alleviate the computational burden of Struggle GA and perform better than standard similarity measures. This is particularly interesting for the scheduling problem in Grid systems, which due to changeability over time, has demanding time restrictions on the computation of planning the jobs to resources.
This work describes Large Eddy Simulation of backward-facing step flow laden with particles. The concentration of the particles in the flow is high enough for consideration of two-way coupling. This means that the particles are influenced by fluid and vice versa. The inter-particle collisions are neglected. The Euler-Lagrange method is adopted which means that the fluid is considered to be continuum (Euler approach) and for each individual particle is solved Lagrangian equation of motion. Particles are considered to be spherical. The simulations are performed for different volume fractions. The results are compared to the single-phase flow in order to investigate the effect of the particles on the turbulence statistics of the carrier phase. and Obsahuje seznam literatury
Mutant Lurcher mice represent an animal model of naturally
occurring cerebellar degeneration. A gene mutation causes the
demise of all Purkinje cells, as along with certain other types, as
well as the functional elimination of the cerebellar cortex.
Involvement in the research using this model of the C3H strain
began at the Department of Physiology, UCL in 1995/96.
It continued in scientific cooperation with other European
laboratories where we obtained Lurcher mice of the B6CBA
strain. The aim of the effort was first to identify the extent to
which the cerebellum is involved in the higher nervous activity,
i.e. cognitive and other functions. In that research, use was
made of an entire array of methodological procedures to examine
learning, memory, motor functions and emotional behavior.
It was completed with an electrophysiological examination of the
brain and special microscopic procedures. The results
demonstrated that the cerebellum (aside from its traditional
tasks) does in fact play a significant role in cognitive function,
emotions, etc. It was further found that the neurodegenerative
processes also affected the immune and endocrine functions,
confirming the concept of the unity of the psychoneuroendocrine-immune system. Surprisingly, despite their
neurological impairment, the affected animals were able to learn
to some extent and, make progress with physical training,
improving not only their motor skills but also learning and
memory, including deferring of signs of aging. These particular
findings may prove useful for human medicine.
The aim of our study was to evaluate the potential differences in blood pressure (BP) profile in subjects with different forms of primary aldosteronism (PA). Simultaneously, we studied the effects of PA treatment on BP curve. We therefore monitored 24-hour ambulatory blood pressure values in 22 subjects with aldosterone-producing adenoma (APA), 22 subjects with idiopathic hyperaldosteronism (IHA) and 33 subjects with essential hypertension (EH) as controls. We found a significantly attenuated nighttime systolic BP decline in the APA group (P=0.02). Patients with IHA had lower nighttime systolic BP values (P=0.01) and also a diastolic BP decline (P=0.02) during the night in comparison with EH. We did not detect any significant differences in BP profile characteristics between APA and IHA. Specific treatment of primary aldosteronism (adrenalectomy, treatment with spironolactone) led to the normalization of the BP curve with a marked BP decline. Our study thus demonstrates a blunted diurnal BP variability in patients with primary aldosteronism the specific treatment of which normalized previously attenuated nocturnal BP fall., T. Zelinka, J. Widimský., and Obsahuje bibliografii
In order to understand friction processes in wheel/rail contact a new experimental device has been developed. Twin-disc approach has been used to determine adhesion curves in wheel-rail contact under various conditions. This paper describes some details about the design of the twin-disc experimental device. Finally, preliminary results are discussed. and Obsahuje seznam literatury
Among the many characterizations of the class of Baire one, Darboux real-valued functions of one real variable, the 1907 characterization of Young and the 1997 characterization of Agronsky, Ceder, and Pearson are particularly intriguing in that they yield interesting classes of functions when interpreted in the two-variable setting. We examine the relationship between these two subclasses of the real-valued Baire one defined on the unit square.
We establish two new norm convergence theorems for Henstock-Kurzweil integrals. In particular, we provide a unified approach for extending several results of R. P. Boas and P. Heywood from one-dimensional to multidimensional trigonometric series.
We prove an extension theorem for modular functions on arbitrary lattices and an extension theorem for measures on orthomodular lattices. The first is used to obtain a representation of modular vector-valued functions defined on complemented lattices by measures on Boolean algebras. With the aid of this representation theorem we transfer control measure theorems, Vitali-Hahn-Saks and Nikodým theorems and the Liapunoff theorem about the range of measures to the setting of modular functions on complemented lattices.