Astronomické informace pro profesionály jsou v dnešní době bez problému dostupné v odborných časopisech, databázích naměřených dat, knihách a internetových publikacích. Kde však může získat kvalitní nezkreslené informace širší veřejnost? Televizních astronomických pořadů je jako šafránu, a ty, které zbyly, jsou mnohdy kombinovány s astrologií, věštectvím a jinými pavědami. V rozhlase zůstaly pořady Meteor a Planetárium, ale ty se netýkají jen astronomie. Z ryze astronomických vědecko-populárních časopisů nám zbyl už jediný - Astropis - a doufejme, že přežije i nadále. Většina lidí se proto obrací k internetu. Pro laika je někdy obtížné odlišit kvalitní informace od balastu, a proto přinášíme čtenářům stručný výběr některých webů s hodnotnými astronomickými informacemi. and Petr Kulhánek.
Level of asymmetric dimethylarginine (ADMA) is elevated and endothelial progenitor cells (EPC) and stem cells (SC) are decreased in patients undergoing renal transplantation (Tx) and may contribute to cardiovascular complications. We tested the hypothesis that ADMA, EPC and SC can be influenced with regular physical exercise early after Tx. Blood samples of ADMA, EPC, SC, adipocytokines and metabolic parameters were randomly obtained from 50 transplant patients before and 6 months after exercise program (Group I). Fifty age, sex HLA typing, duration of dialysis and immunosupression regimen-matched non exercising transplant were examined as controls (Group II). After 6 months, in Group I ADMA decreased (3.50±0.45 vs 2.11±0.35 μmol/l, P<0.01) and was lower comparing to Grou II (P<0.01), SC and EPC also decreased (2816±600 vs 2071±480 cells/ml resp. 194±87 to 125±67 cells/ml, P<0.02). Next changes in Group I: adiponectin (P<0.01), leptin (P<0.01), resistin (P<0.02). Visfatin, blood lipids, HbA1c, insulin and blood pressure were also influenced by training program (P<0.05)., V. Teplan, I. Králová Lesná, J. Piťha, A. Mahrová, J. Racek, I. Valkovský, A. Sekerková, M. Štollová., and Obsahuje bibliografii
A recently discussed cardiovascular risk factor, asymmetric dimethylarginine (ADMA), is known to act as an endogenous inhibitor of endothelial nitric oxide synthase. The aim of this study was to establish 1) the relationship between ADMA and ultrasonographically or biochemically determined endothelial dysfunction in children, and 2) the effect of folate supplementation on these parameters. The study cohort included 32 children with familial hypercholesterolemia (FH), 30 with diabetes mellitus type 1 (DM1) and 30 age-matched healthy children as the control group. Furthermore, twenty-eight randomly selected FH and DM1 children were re-examined after 3-months supplementation with folic acid. Baseline levels of ADMA and oxidized low density lipoproteins (oxLDL) were significantly higher in FH group than in DM1 and healthy children. Children in DM1 group had significantly lower concentration of homocysteine, but ADMA levels were normal. Folic acid supplementation significantly lowered homocysteine and hsCRP levels in both FH and DM1 group; however, ADMA and oxLDL concentrations remained unaltered. In conclusion, ADMA and oxLDL appear to be associated with endothelial dysfunction in children with FH. Administration of folic acid did not influence these markers in both FH and DM1 children., P. Jehlička ... [et al.]., and Obsahuje seznam literatury
The gob side entry retaining with high water material is often used in coal mines. To study the stress evolution characteristics of surrounding rock and asymmetric support control technology of gob side entry retaining with high water material, the evolution law of stress and deformation of surrounding rock in gob side entry retaining during working face mining is studied by theoretical analysis, numerical simulation and field measurement. According to the stress variation of overlying strata during the mining process of the working face, the mechanical models before and after the basic roof fracture were established respectively. The stress and deformation of the filling body and the roof on the side of the filling body are larger, and the stress and deformation of the solid coal and the roof on the side of solid coal are smaller. The maximum stress is at 3 m away from the roadway. The first weighting step distance is 40 m and the periodic weighting step distance is 30 m. Based on the stress and deformation characteristics of the roadway surrounding, the roadway surrounding support is divided into filling bodyside, solid coal side, and middle part of roadway roof. The asymmetric support technology of "filling body+ double row hydraulic prop+ I-beam+ high-strength pretension anchor cable+ high-strength bolt" is proposed. The field engineering practice shows that the surrounding rock control effect of asymmetric support technology with high water material is good., Qiyuan Shan, Yongli Liu, Tao Li and Zhupeng Jin., and Obsahuje bibliografii