Mezi většinou opomíjené artefakty, běžně nacházené na pravěkých sídlištích, patří hliněná závaží. Jejich podrobná analýza přitom může přispět k řešení mnoha důležitých otázek, jakými jsou technologie výroby keramiky a textilu, zacházení s odpadem, depoziční a postdepoziční procesy apod. Soubor závaží, který umožňuje položení takových otázek, pochází ze sídliště z mladší doby bronzové, zkoumaném v l. 2005–2009 v jihočeské Březnici. Ve dvou specifických žlabovitých objektech byly odkryty dva hromadné nálezy několika desítek kusů závaží, které byly v předložené studii podrobeny detailní archeologické i archeobotanické tech, stejně jako položení otázky o způsobech a důvodech jejich hromadného uložení v zmíněných žlabech. and Clay weights rank among frequently neglected artefacts commonly found at prehistoric settlements. However, their detailed analysis could in fact contribute to the resolution of numerous important questions, including the production technology of pottery and textiles, the handling of waste, depositional and post-depositional processes and others. An assemblage of weights that allows such questions to be raised comes from the Late Bronze Age settlement investigated in south Bohemian Březnice in 2005–2009. Two mass finds of several dozen weights found in two specific trench-like features were subjected to a detailed archaeological and archaeobotanical analysis. These analyses make it possible to study the role and purpose of these artefacts in societies at the time and to ask questions concerning how and why their mass deposition was made in the aforementioned trenches.
Previous observation demonstrated that measured nucleolar and nuclear diameters and the resulting calculated ratio might facilitate estimation of the approximate size of the nuclear region occupied by the nucleolar bodies. The size of nuclear regions occupied by nucleolar bodies decreased during the differentiation and maturation of leukaemic lymphocytes, but was constant for each differentiation or maturation stage. The present study was
unde-taken to provide more information on the approximate size of the nuclear regions occupied by nucleolar bodies in leukaemic granulocytic progenitors. Myeloblasts of established Kasumi 1 and K 562 cell lineages originating from human myeloid leukaemias were convenient models for such study because they represented only one and early differentiation stage of granulocytic progenitors. According to the results, the maximal and mean nucleolar body : maximal and mean nuclear diameter ratios in myeloblasts without heavy nuclear alterations were stable and not markedly influenced by the anti-leukaemic treatment or aging. Thus, the roughly estimated size of nuclear regions occupied by nucleolar bodies in these cells appeared to be similar and stable regardless of aging or antileukaemic treatment. In contrast, the antileukaemic treatment or aging in such myeloblasts induced marked reduction of the nucleolar biosynthetic activity reflected by the decreased number of nucleolar fibrillar centres. and Corresponding author: Karel Smetana
We derive the phenomena of Landau damping as a stationary point of entropy functions with Lagrangian methods. The steady states are described inside of some interval of numbers with infinite fuzzy logic controllers. The results are also true for local equilibriums, i.e. for some global non-equilibriums functions.
Hypertrophied hearts are known for increased risk of arrhythmias and are linked with reduced ischemic tolerance. However, still little is known about state characterized only by increased left ventricle (LV) mass fraction. Seventeen isolated rabbit hearts with various LV mass were divided into two groups according to LV weight/heart weight ratio (LVW/HW ratio), namely group H and L (with higher and lower LVW/HW ratio, respectively) and underwent three short cycles of global ischemia and reperfusion. The differences in electrogram (heart rate, QRSmax, mean number, onset and dominant form of ventricular premature beats) and in biochemical markers of myocardial injury (creatine kinase, lactate dehydrogenase - LDH) and lipid peroxidation (4-hydroxy-2-nonenal - 4-HNE) were studied. As compared to group L, hearts in group H exhibited lower tolerance to ischemia expressed as higher incidence and severity of arrhythmias in the first ischemic period as well as increase of LDH and 4-HNE after the first reperfusion. In the third cycle of ischemia-reperfusion, the preconditioning effect was observed in both electrophysiological parameters and LDH release in group H. Our results showed consistent trends when comparing changes in electrograms and biochemical markers. Moreover, 4-HNE seems to be good potential parameter of moderate membrane alteration following ischemia-reperfusion injury., M. Hlaváčová, V. Olejníčková, M. Ronzhina, T. Stračina, O. Janoušek, M. Nováková, P. Babula, J. Kolářová, I. Provazník, H. Paulová., and Obsahuje bibliografii