Quaternary faulting in the western part of the Gulf of Corinth has been evidenced by geology and geomorphology, as well as by seismic recording. A series of three main normal fault segments are aligned in a steep southern coastal zone of the gulf. These fault segments, 15 to 25 km long, have an average strike of 90° - 105° and a northward dip of about 50° - 75°. Selected fault points were equipped with 3-D crack gauges TM71 during 2002 to monitor movements along the fault planes here, as well as on another fault cutting through the small island of Trizonia near the opposite northern shore of the gulf. Results of the monitoring present relative displacements induced by active tectonic movement s. Generally, the movements recorded on the faults are characteristic of an aseismic linear creep in vertical, i.e. upliftin g/subsiding in rates of mm per year due to uplifts of the Peloponnesian Peninsula. In 2003 a thr ee months long period of fast acceleration of movements was recorded. During this acceleration phase displacements changed to skew uplifting/subsiding with a left-lateral horizontal component. Moreover, horizontal rotation of monitored blocks corresponding to a sy stematic westwards opening of the Gulf was observed with only single eastward opening episodes., Josef Stemberk and Blahoslav Košťák., and Obsahuje bibliografické odkazy
a1_Patients with chronic kidney disease (CKD) have an increased risk of premature mortality, mainly due to cardiovascular causes. The association between hemodialysis and accelerated atherosclerosis has long been described. The ankle-brachial index (ABI) is a surrogate marker of atherosclerosis and recent studies indicate its utility as a predictor of future cardiovascular disease and all-cause mortality. The clinical implications of ABI cut-points are not well defined in patients with CKD. Echocardiography is the most widely used imaging method for cardiac evaluation. Structural and functional myocardial abnormalities are common in patients with CKD due to pressure and volume overload as well as non-hemodynamic factors associated with CKD. Our study aimed to identify markers of subclinical cardiovascular risk assessed using ABI and 2D and 3D echocardiographic parameters evaluating left ventricular (LV) structure and function in patients with end-stage renal disease (ESRD) (patients undergoing dialysis), patients after kidney transplantation and non-ESRD patients (control). In ESRD, particularly in hemodialysis patients, changes in cardiac structure, rather than function, seems to be more pronounced. 3D echocardiography appears to be more sensitive than 2D echocardiography in the assessment of myocardial structure and function in CKD patients. Particularly 3D derived end-diastolic volume and 3D derived LV mass indexed for body surface appears to deteriorate in dialyzed and transplanted patients. In 2D echocardiography, myocardial mass represented by left ventricular mass/body surface area index (LVMI) appears to be a more sensitive marker of cardiac structural changes, compared to relative wall thickness (RWT), left ventricle and diastolic diameter index (LVEDDI) and left atrial volume index (LAVI)., a2_We observed a generally favorable impact of kidney transplantation on cardiac structure and function; however, the differences were non-significant. The improvement seems to be more pronounced in cardiac function parameters, peak early diastolic velocity/average peak early diastolic velocity of mitral valve annulus (E/e´), 3D left ventricle ejection fraction (LV EF) and global longitudinal strain (GLS). We conclude that ABI is not an appropriate screening test to determine the cardiovascular risk in patients with ESRD., Magdaléna Kovářová, Zuzana Žilinská, Ján Páleš, Zuzana Kužmová, Andrea Gažová, Juraj Smaha, Martin Kužma, Peter Jackuliak, Viera Štvrtinová, Ján Kyselovič, Juraj Payer., and Obsahuje bibliografii
During routine processing of selected events of an active KTB experiment it has appeared doubts concerning data reliability and consequently the reliability of results based on them. In the paper 3 events are studied in detail, full seismic moment tensors, as well as their errors, are determined (by non-linear inversion of P/SH waves ratios). It is shown that for the processed low constrained data moment tensor (MT) can be determined, however the relative error is of order of first tens of percent; the results also considerably depend on the way of data picking, used medium model, way of Cost function construction, etc. Any subsequent geophysical interpretation therefore should takes into account this uncertainty. MTs are finally decomposed into DC and non-DC parts, MTs errors are also transformed., Petr Kolář., and Obsahuje bibliografii
3D microscopy and image analysis provide reliable measurements of length, branching, density, tortuosity and orientation of tubular structures in biological samples. We present a survey of methods for analysis of large samples by measurement of local differences in geometrical characteristics. The methods are demonstrated on the structure of the capillary bed in a rat brain., J. Janáček ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy
The present paper concerns long-term 3D monitoring of active fault structures in the Krupnik-Kresna seismic zone, SW Bulgaria with the use of extensometers TM71. The purpose is to establish the real rates of fault movements in the most seismically active area in Bulgaria. Three points were installed (B6 on Krupnik Fault, and K5 and K12 on Struma Fault), which indicate a recent activity. The fault movements are characteristic with “calm” periods, linear slips, accelerations and sudden displacements. Different regimes of dynamics have been established corresponding to different periods. The greatest dynamics is found at monitoring point B6 along Krupnik Fault: for the whole period of observation the trends are calculated as left lateral slip with 1.88 mm/a and a thrusting with 1.59 mm/a with high correlation coefficients. Co-seismic displacements from local and distant earthquakes were recorded. The significant impact was from M=7.4, 17 August, 1999, Izmit Earthquake, Turkey, showing a shortening of 8.34 mm, a right-lateral slip of 5.09 mm and a thrusting of 0.96 mm. After that, for a short period of time the regime of movement on fault was changed. Movements on the Struma system reveal lower rates. Both points show left-lateral movements, 0.28 mm/a at K5 and 0.09 mm/a at K12, and thrusting with 0.11 mm/a at K5 and 0.72 mm/a at K12., Nikolai Dobrev., and Obsahuje bibliografii
The present paper shows the results of 3D monitoring with the use of extensomet ers TM71 performed in Bulgaria in the framework of COST Action 625. This research was performed in selected areas: Simitli graben that is the most seismoactive area in Bulgaria; Madara plat eau - rock scarp with historical monument affe cted by rock toppling; East Rhodopes area - a possibly active fault zone and a large landslide. The most impressive results were established at Simitli graben area with the rate of 2.73 mm/year sinistral movement of Krupnik Fault. Local earthquakes located at NE part of the graben usually influence the movements along this fault. An acceleration of the left latera l movements during calm periods has been established, and respectively, the movements stop (or going in opposite direction) during seismic activity. At Madara site, the results from the 15 years monitoring show subsidence of rock s lices by 0.9 mm per year and si milar rate movement of the slices to South direction. Influence from Izmit earthquake, Vrancea earthquakes and local ones have been established. The monitoring of the fault at General Geshe vo Village, East Rhodopean area started in 2003. The first results show mainly gravitational movements - subsidence of NE block 1.5 mm/year., Nikolai Dobrev and Elka Avramova-Tacheva., and Obsahuje bibliografické odkazy
The paper presents the results of geodyn amic research in the fram e of the project COST 625 relating to active tectonic structures’ monitoring on the selected areas in Poland, Italy and Greece. Research was realised using a self-developed control and measurement system. The resu lts of researches for period 2000-2006 indi cate slight movements of observatio n points in the Sudety Mts. reaching several millimetres. However, the results confirm recent mobility of tectonic structures o f this area. Research realised in the Mediterranean Region objects - Gargano, Norcia (Italy) and Kaparelli (Greece) - indicate movements of observation points reaching over a dozen millimetres, particularly on the Gargano area. Continuation of cyclic control measurements on these objects is fully justified ., Stefan Cacoń, Bernard Kontny and Jarosław Bosy., and Obsahuje bibliografické odkazy
In the rat model, 6-hydroxydopamine (6-OHDA) known as a selective catecholaminergic neurotoxin used chiefly in modeling Parkinson's disease (PD). Continuous aerobic exercise and curcumin supplementations could play a vital role in neuroprotection. This study aimed to explore the neuroprotective roles of regular aerobic exercise and curcumin during PD. For this, rats were treated as follows for 8 consecutive weeks (5 d in a week): For this, animals were orally treated with curcumin (50 ml/kg) alone or in combination with aerobic exercise. Compared with a control group, induction of PD by 6-OHDA increased the amount of α-synuclein protein and malondialdehyde levels and decreased the number of substantia nigra neurons, total antioxidant capacity, and glutathione peroxidase activity in brain tissue. All these changes were abolished by the administration of curcumin with aerobic exercise treatments. Activity behavioral tests also confirmed the above-mentioned results by increasing the rod test time and the number of rotations due to apomorphine injection. Histopathology assays mimic the antioxidant activity and behavioral observations. Combined curcumin with aerobic exercise treatments is potentially an effective strategy for modifying the dopaminergic neuron dysfunction in 6-OHDA-induced rats modeling PD via dual inhibiting oxidative stress indices and regulating behavioral tasks.