The primary aim was to determine frequencies of mutations related to risk of venous thrombosis in healthy Caucasians in Central Bohemia. In a cohort of 1527 healthy individuals the frequency of risk alleles for the mutations FV Leiden and FII 20210G>A was 4.5 % and 1.3 %, respectively. Frequency of 4G PAI-1 allele was 55.5 %. Genotype frequencies were: GG 91.03 %, GA 8.91 %, an d AA 0.07 % for FV Leiden; GG 97.45 %, GA 2.49 %, and AA 0.07 % for FII 20210G>A; 4G/4G 30.26 %, 4G/5G 50.56 %, and 5G/5G 19.19 % for PAI-1. Frequency of the risk allele A in polymorphism SERPINC1 (IVS +141G >A) was 11.3 %, and frequencies of genotypes were as follows: GG 78.36 %, GA 20.66 %, and AA 0.98 %. Frequency of the risk allele T for polymorphism GP6 13254T>C was 87.7 %, and frequencies of genotypes were as follows: TT 77.14 %, TC 21.15 %, and CC 1.70 %. Frequency of the risk allele A in polymorphism CYP4V2 (Lys259Gln ) was 65.2 %, and frequencies of genotypes were: CC 12.25 %, CA 45.12 %, and AA 42.63 %. All observed genotypes and alleles frequencies were without gender differences. Their occurrences confirm a relatively high prevalence of hereditary thrombophilia predisposition in the Czech Republic., T. Kvasnička ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy
A mineralogical study of the weathering crusts rich in P and Mn from the locality Hodušín - Božetice at Milevsko is presented. The locality belongs to the central part of the variegated group of Sušice and Votice in the Moldanubian Unit. From the analytical methods used, the IR-spectroscopy yielded satisfactory results. The main crust components subjected to weathering are apatite (of a CarHap B - dahllite type) and Mn-minerals (massive black psilomelane, the needle-aggregates probably comprise a poorly recrystallized psilomelane). Disintegrated rocks consist of a mixture of clay minerals, calcite and relicts of primary minerals (quartz, K-feldspars, albite, pyroxene and rutile). The origin and the source material of these crusts rich in P and Mn can not be unambiguously determined. Apatites without CL-effects indicate that the weathering crusts have originated in a strongly oxidative environment. Well documented neighbouring occurrences of phosphate minerals in the variegated group of Sušice and Votice are associated with graphitic rocks. Optical and quantitative chemical analyses of the rocks suggest that the source of apatite could possible be calc-silicate rocks (erlans) close to the graphitic rocks. Hypothetically, the metaphosphorite layers in the variegated Moldanubian Unit can also be considered a possible source of phosphorus., M. Brož, M. Kovářová, Z. Losos, M. Linhartová and V. Vávra., and Obsahuje bibliografii
The remarkable progress in laser technology leads also to a development of techniques of time-resolved optical spectroscopy. The ultrafast laser spectroscopy in the visible spectral region can be now used for investigation of rapid processes with the time resolution of about 10 fs. This paper reviews the experimental background and typical techniques of ultrafast laser spectroscopy. The potentional of ultrafast spectrocopy is illustrated with the results obtained by authors in the field of ultrafast relaxation processes in semiconductors and semiconductor nanostructures., Petr Malý, Petr Němec, František Trojánek., and Obsahuje bibliografii
Polarografická metoda umožňuje studium řady fyzikálněchemických problémů. Jsou uvedeny příklady z oblasti výzkumu struktury fázového rozhraní elektroda/roztok, adsorpce na povrchu elektrody, elektrochemického fotoefektu, fázových přechodů povrchových filmů, přenosu elektronu na molekulární vzdálenosti a oscilačních elektrochemických systémů., Polarography is a suitable method for solving numerous problems of physical chemistry. Examples from the following fields are given: structure of electrode/solution interfaces, adsorption on electrode surface, electrochemical photo-effect, phase transition of surface films, electron transfer over molecular distances, and electrochemical oscillating systems., Lubomír Pospíšil., and Obsahuje bibliografii
Alena Fialová (ed.) ; redaktoři: Alena Fialová (próza), Petr Hruška (poezie), Lenka Jungmannová (drama)., Obsahuje bibliografie, bibliografické odkazy a rejstřík., and Anglické resumé
Ernst Mach was already an internationally recognised experimental physicist, when he, after professorships for Mathematics and Physics in Graz and Experimental Physics in Prague, took over the chair for "Philosophy, particularly for the History and Theory of the Inductive Sciences", at the University of Vienna in 1895. This turn from natural sciences to philosophy was really an exception in the academic field. Although he was not a specialist in philosophy his ideas exhibited a remarkable influence. Here is the first part of the author's text, the second, closing part (Mach and Philosophy) will be published in the next issue of this Journal., Friedrich Stadler ; z angličtiny a němčiny přeložil M. Černohorský., and Obsahuje bibliografii
A major reform in the reign of Joseph II was the establishment in 1786 of the provincial building directorates, through which the court aimed to regulate all public building works in the monarchy. Although the original aim of unifying building regulations throughout the realm was never achieved, the reform was a success and remained in force, with a few minor amendments, until the revolutionary year of 1848. One reason for its success was the elite corps of civil engineers who staffed these institutions. This study looks at advances in technical education, especially engineering, in the Habsburg monarchy from the beginning of the 18th century and the emergence of the Collegia Nobilia, or elite colleges, where graduates were prepared for a career in the Imperial Army. Besides military architecture, the colleges also taught the fundamentals of civil engineering, turning out some of the best‐trained creators of early modern architecture. The development and nature of this elite engineering training is examined with reference to the engineering academies of Prague, Vienna and Olomouc. In all three cases we stress the colleges’ status within the state framework, and their evolution in the light of changing official doctrine and methods of instruction. In all three cases it is clear that during the latter half of the 18th century the original ‘aristocratic’ colleges began to decline and were slowly replaced by similar state‐controlled establishments. As a first step, the court of Joseph II introduced a specialized course in practical architecture at the Vienna Academy of Fine Arts. From around 1800 this model was gradually superseded by the progressive French‐style polytechnic, a modified version of which remains the standard model for technical education to this day., Michal Konečný., and Obsahuje bibliografické odkazy