1) Alloxystinae are major secondary parasitoids of aphids, important in both their ecology and pest management. 2) Two radically differing views of alloxystine taxonomy exist in the literature, in one of which the group is very diverse, in the other it consists of a few variable species. 3) We sequenced a variable nuclear gene region (ITS2) for 28 specimens of a morphologically clearly defined group which, in one view belong to a single species and in the other to four species. We find that the four putative species each carry a different unique allele with no intraspecific variation. We show that the probability of the observed distribution of alleles under the assumption of a single interbreeding population is very small and we reject the view that all specimens belong to a single biological species. 4) We discuss the implications of our results for aphid - parasitoid community ecology and the biological control of aphids with parasitoids.
The main purpose of the research was to determine the conditions affecting ice phenomena, including the three-phase cycle of ice: expansion, retention and decay of the ice cover on selected rivers of the Baltic coastal zone in the Northern Poland (Przymorze region). The analysis has been elaborated for the years 1951–2010 against the backdrop of currently occurring climatic changes, with particular emphasis on the development and phase variability of the NAO. The article presents the impact of the variability in atmospheric circulation which has manifested in an increase in air temperature, over the last 20 years, on thermal conditions during winter periods in the South Baltic Coastal Strip. The increase in air temperature has contributed to an increase in the temperature of river waters, thus leading to a shortening of the duration of ice phenomena on rivers in the Przymorze region. The article also brings to light an increased occurrence of winter seasons classified as cool, and a disruption in the occurrence of periods classified as normal over the last 30 observed years. The research has demonstrated a significant dependence between the seasonal change in air temperature and the variability of thermal conditions of water, which has a direct impact on the variability of the icing cycle of rivers in the Przymorze region. The authors also show that the variability in forms of ice phenomena for individual river sections is determined by the local factors, i.e. anthropogenic activity, impact of urbanized areas or inflow of pollutants.
From photometric and spectrographic observations of the runaway star 53 Ari we confirm that the star did noat exhibit detectable light- and radial velocity variations. The star is definitely not a beta Cephei star.
I. The mean state of circulation in some of the months can be demonstrated by the mean position of the frontal zone. From the position of the frontal zone we can determine if the zonal or meridional circulation prevails, and in which way it will change during the year
II. The long-range variation of the mean frontal zone in relation to solar activity expressed by Ejgenson s Index of Recurrency of Sunspots A is determined. The effect ascertained is especially significant in January. The results in maps show the deviations of frequencies of the zones from the mean state, partly in the years of minima, partly in the years of maxima of the recurrency of sunspots.
Introduction: Ankylosing spondylitis (AS) is an inflammatory rheumatic disease characterized by the development of osteoproductive changes in the spine which could possibly result in ankylosis. Treatment with tumour necrosis factor alpha (TNFα) inhibitors has proved to be an important step forward in the treatment of this disease, but for the time being it is not clear whether it favourably influences radiographic progression of the disease. Vascular endothelial growth factor most probably plays a role in the development of osteoproductive changes and recently its predictive influence on radiographic progression has been demonstrated. Bone morphogenic protein 2 (BMP-2) participates in the regulation of bone proliferation and its increased serum level has been demonstrated in patients with advanced AS and correlated with the degree of radiographic changes. Aim: The study aims to evaluate the VEGF and BMP-2 levels in patients with ankylosing spondylitis and how these levels relate to the concurrent treatment with TNFα inhibitors. Methods: Sera were evaluated from patients at the Rheumatologic Clinic of the Hradec Králové Faculty Hospital who fulfilled the modified New York Criteria for AS (n = 55). In these patients, the parameters of the activity of the disease (BASDAI = Bath Ankylosing Spondylitis Disease Activity Index, CRP = C-reactive protein) and the concurrent therapy (TNFα inhibitors, n = 21, vs. non-anti TNFα, n = 34) were recorded. The levels of VEGF and BMP-2 were analyzed using the ELISA method. Results: In patients treated with TNFα inhibitors, a significantly lower VEGF level was found when compared to untreated patients (140.3 (109.4; 262.2) vs. 261 (172.4; 396.6) pg/ml; p = 0.02). No difference was found between BMP-2 levels in both groups (treated vs. untreated patients) (254.8 (2301; 267.3) vs. 261.1 (248.6; 273.5) pg/ml; p = 0.24). A correlation analysis did not reveal any relationship between VEG F and BMP-2 (r = 0.057; p = 0.68). Serum levels of VEGF correlated with serum levels of CRP (r = 0.56; p = 0.00001) and the BASDAI value (r = 0.33; p = 0.015). Conclusion: Significantly lower VEGF levels were found in patients treated with TNFα inhibitors versus the untreated patients. These findings are in harmony with some hitherto published analyses and may give evidence of a favourable effect of TNFα inhibitors on radiographic progression. Neither influence on the BMP-2 level by treatment with TNFα inhibitors nor correlation with VEGF levels was demonstrated. and M. Tošovský, P. Bradna, C. Andrýs, K. Andrýsová, E. Čermáková, T. Soukup
Both the Czech and Slovak Republic announced their plans to play an important role in the processof “nuclear renaissance” in Central Europe. However, this process cannot be limited to a mere multiplicationof nuclear facilities, but must be accompanied by strengthening of the legal and regulatory framework. Takingthe potential magnitude of a nuclear incident into regard, strengthening of the existing legal framework forthe nuclear third party liability must play an eminent role in this legislation. This paper deals with the currentliability frameworks in both countries, analysing the implementation of their commitments arising from theVienna Convention on Civil Liability for Nuclear Damage of 1963. Further, it points out major challengesfor the future development in this field, in particular taking the provisions of the Protocol to Amend the ViennaConvention on Civil Liability for Nuclear Damage of 1997 into regard.
The visual observations of the soviet artificial satellites made in ČSR or by czechoslovak observers during the IGY (to the end of 1958) are collected. AU these data were sent to the IGY regional centre at Moscow. The list of the observing stations is added, too. and Edited by V. Guth and L. Sehnal
The classical Vitali convergence theorem gives necessary and sufficient conditions for norm convergence in the space of Lebesgue integrable functions. Although there are versions of the Vitali convergence theorem for the vector valued McShane and Pettis integrals given by Fremlin and Mendoza, these results do not involve norm convergence in the respective spaces. There is a version of the Vitali convergence theorem for scalar valued functions defined on compact intervals in Rn given by Kurzweil and Schwabik, but again this version does not consider norm convergence in the space of integrable functions. In this paper we give a version of the Vitali convergence theorem for norm convergence in the space of vector-valued McShane integrable functions.
Von Willebrand disease is a commonly inherited bleeding disorder caused by defects of von Willebrand factor (vWF). In the most common valve diseases, aortic valve stenosis (AVS) and mitral valve regurgitation (MVR), a bleeding tendency has been described in a number of patients. This has been associated to a high turbulence of blood flow through the compromised valve, promoting degradation of vWF with loss of high-molecular-weight multimers of vWF (HMWM), leading to an acquired von Willebrand syndrome (AvWS). We analysed three groups of patients, one affected by AVS, treated with transcatheter aortic valve implantation (TAVI), the second group of patients affected by MVR, treated with Mitraclip® mitral valve repair. The third group was represented by patients also affected by AVS, but not eligible for TAVI and treated with standard surgery. A fourth group of patients that underwent percutaneous coronary intervention (PCI) with stenting was used as a control. Our results demonstrated that the level of vWF measured as antigen concentration (vWF:Ag) increases in all cohorts of patients after treatment, while in control PCI patients, no modification of vWF:Ag has been registered. Western blot analysis showed only a quantitative loss of vWF in the pre-treatment time, but without significant HMWM modification. The monitoring of the vWF:Ag concentration, but not the quality of HMWM, can indicate the status of blood flow in the treated patients, thus introducing the possibility of using the vWF antigen detection in monitoring the status of replaced or repaired valves.