The general author‘s mesomechanical model with tensorial internal variables is applied to creep of steel 0,5Cr0,5Mo0,3V under different loading levels. It is shown that the creep process can be described by the mesomechanical model in its whole course up to rupture. However, the model parameters can be influenced at the very beginning by the application of the applied load if it is high enough to cause changes in the internal structure. This problem is specific for creep at high temperatures and significant differences in the loading levels (contrary to the small-strain plasticity studied usually at low temperatures, where the model parameters can be considered the same for different loadings). and Obsahuje seznam literatury