In this paper, for the impulsive fractional integro-differential equations involving Caputo fractional derivative in Banach space, we investigate the existence and uniqueness of a pseudo almost periodic PC-mild solution. The working tools are based on the fixed point theorems, the fractional powers of operators and fractional calculus. Some known results are improved and generalized. Finally, existence and uniqueness of a pseudo almost periodic PC-mild solution of a two-dimensional impulsive fractional predator-prey system with diffusion are investigated., Zhinan Xia., and Obsahuje bibliografii