We reviewed 37 studies on vegetation succession in which the succession started on bare ground, was followed in at least six sites, and where these sites were spatially separated over at least 10 km2. The effect of environmental factors, which were explored in at least five studies, on the course of succession was assessed, based on the proportion of significant and non-significant results. Surrounding vegetation, macroclimate, soil moisture, amount of nitrogen and soil texture appeared to have the highest influence on the course of succession. Less influential were the size of a disturbed site, pH, organic matter and phosphorus content. Surrounding vegetation exhibited a significant effect in all cases where this was considered. These results imply that succession cannot be studied without the landscape context. The large-scale approach to succession has the potential to contribute substantially to both the theory of succession and practical applications, especially in restoration ecology.