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28542. Uptake, reflux, and excretion of bromosulfophthalein in ischaemia-reperfusion injury of rat liver

Creator:
Kukan, M., Bezek, Š., and Trnovec, T.
Type:
article, model:article, and TEXT
Subject:
ischaemia, reperfusion, liver, and bromosulfophthalein uptake, reflux, excretion
Language:
English
Description:
The uptake, reflux and excretion of bromosulfophthalein (BSP) were studied on a model of total warm ischaemia for 30 min (group 1) or 60 min (group 2) followed by reperfusion for 45 min in the isolated perfused rat liver of unfasting rats. In group 1, the BSP hepatic uptake was comparable to control livers (30 s ischaemia plus 45 min reperfusion), but was significantly reduced in group 2. The reflux of BSP from liver to perfusate in group 1 and group 2 resulted in the appearance of secondary concentration time peaks of BSP in the reservoir perfusate. This result suggests that ischaemia-reperfusion induced a qualitative change in BSP pharmacokinetics. Excretion of the dye into bile was significantly impaired in group 2 only. The leakage of lactate dehydrogenase into the perfusate was increased moderately in both group 1 and group 2 in comparison to the controls, suggesting a low degree of liver parenchymal injury. In conclusion, the results of this investigation showed that BSP pharmacokinetics were not only undergoing quantitative changes but also a qualitative change in the model of ischaemia-reperfusion injury of the liver obtained from fed rats and may thus serve as a highly sensitive indicator of liver viability.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

28545. Úraz podtlakem v bazénu: etiologie, prevence a management

Creator:
Škach, Jiří, Kašák, Petr, and Šrám, J.
Format:
print, text, and regular print
Type:
model:article, article, Text, kazuistiky, and TEXT
Subject:
rány a poranění--etiologie, plavecké bazény, kompartment syndrom--etiologie--terapie, vnitřnosti--zranění, úrazy a nehody, lidé, mužské pohlaví, and mladý dospělý
Language:
Czech and English
Description:
Úraz podtlakem v bazénu je skupina specifických raritních poranĕní s velkým rizikem fatálních důsledků. Častĕjší obĕtí s častĕji vážnějšími důsledky jsou zejména malé dĕti. Při tomto druhu poranĕní dochází ve vĕtší či menší míře k tonutí postiženého. Případ 19-letého pacienta zachyceného v oblasti hýždí nezajištěným otvorem sací drenáže zajímavĕ ilustruje nĕkteré zvláštnosti této problematiky. Preventivní opatření jsou v současnosti již známá, problém bývá vĕtšinou s jejich důslednou aplikací. K fatálním příčinám patří kromĕ utonutí, hypovolemický šok z náhlé redistribuce tekutin třetího prostoru a eviscerace s devastací vnitřních orgánů. Lokalizované často bizardní a velké otoky a sufúze lze v naprosté vĕtšinĕ případů řešit konzervativnĕ. Pro prevenci je klíčové rozšíření informace o existenci těchto poranĕní do obecného povědomí. Pro jejich správný management je pak důležité prohlubování povědomí a sdílení zkušeností s řešením těchto raritních poranĕní v odborné veřejnosti., Swimming pool suction injuries are unique and rare with a substantive risk of fatal consequences. Little children under the age of 8 are the most frequent victims with serious injuries. Drownings of different seriousness are also a usual part of accidents. The case of a 19 year old man trapped in the gluteal area by a unsecured suction drainage hole illustrates the uniqueness of this problem in an interesting way. Prophylactic arrangements are well known but the problem is with their strict application. Fatal causes excluding drowning include hypovolemic shock from the sudden redistribution of intersticial fluid and blood and also the evisceration of the bowel and other abdominal organs. Localised often bizarre and large swellings and sufusions can be treated nonoperatively in the vast majority of cases. For the prevention of these injuries it is important to inform the public and increase their awareness to these injuries. It is also crucial for the correct management of these injuries a deeper awareness of this issue and a sharing of experiences and solutions with other experts., and J. Škach, P. Kašák, J. Šrám
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

28546. Urban Place as a Heterochronotopia: A Case Study of a Brno Locality

Creator:
Osman, Robert, Seidenglanz, Daniel, and Mulíček, Ondřej
Type:
article, model:article, and TEXT
Subject:
place, heterotopia, heterochronia, heterochronotopia, and Brno
Language:
Czech
Description:
This article is based on long-term study of the relationship between time and space. It does not conceive space as a dimensionless, empty, and homogeneous container but draws instead on the concept of place as unique and meaningful. The conceptualisation of place is thus based on the classic works of the humanist geographers Yi-Fu Tuan and Edward Relph, who consider place to be integral, enclosed, and determinable. The issue of the determinability of integral and still meaningful place is examined using Michel Foucault’s concept of heterotopia. A certain place in a city is linked to a number of other places, which in a way then become present in that place. The place cannot be considered a homotopia but, on the contrary, is a heterotopia. Place can also be conceived from a temporal point of view. Various times (rhythms) blend in a place and they refer to processes that were taking place in other (even temporally very remote) times. Similarly, just as place can be spatially considered a heterotopia, temporally it may be considered a heterochronia. The term heterochronotopia is used to refer to a place that opens out both spatially to other places and temporally to other times. Empirically the article focuses on one selected place in the post-socialist and post-industrial city of Brno (Czech Republic). The article seeks to (1) identify links connecting the researched place to other sites and times and to (2) describe the selected place as a system of associations. The research combines a very wide range of methods such as direct observation, informal interviews, and analyses of historical documents, photos, public transport timetables, etc. The article thus offers an example of a dense description of a place as a temporally or spatially undeterminable entity, provides material for critical reflection on the assumption that urban place is enclosed and determinable, and introduces ‘heterochronotopia’ as a new concept referring to a spatially and temporally undetermined place in a contemporary city.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

28547. Urbanizace chudoby v rozvojových zemích: Regiony "desakota"

Creator:
Kubelková, Jana
Type:
article, model:article, and TEXT
Language:
Czech
Description:
Urbanization of poverty in developing countries. Urbanization of poverty is a complex process which includes various interactions between poverty and growth of urban population. In quantitative terms, it reflects not only the rural-urban migration but also the growth of cities associated with the incorporation of surrounding rural areas and natural population increase within the cities. Moreover, it also includes many important qualitative changes resulting from different nature of rural and urban lifestyles.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

28548. Urbanization causes shifts in species trait state frequencies

Creator:
Knapp, Sonja, Kühn, Ingolf, Wittig, Rüdiger, Ozinga, Wim A., Poschlod, Peter, and Klotz, Stefan
Type:
article and TEXT
Subject:
compositional data, plant traits, species distribution patterns, urban ecology, urban flora, and vascular plants
Language:
English
Description:
Urbanization is one of the most extreme forms of land transformation. It is supposed to change the frequencies of species trait states in species assemblages. We hypothesize that the flora of urban and rural areas differs in the frequency of trait states and ask which traits enable a plant to cope with the urban environment. We tested our hypothesis in Germany, which was divided into grid-cells of ca 130 km2. We distinguished urbanized (with more than 33% urban land use; n = 59), agricultural (with more than 50% agricultural land use; n = 1365) and semi-natural (with more than 50% forest and semi-natural land use; n = 312) grid-cells and calculated the proportions of plant species per trait state in each grid-cell. Multiple linear regressions explained the log-transformed ratio of one proportion to another with land use (urban, agricultural, semi-natural) and the environmental parameters (climate, topography, soils and geology). Additionally, linear mixed effect models accounted for the effects of land use and biogeography and differences in sample size of the three grid-cell types. Urbanized and rural areas showed clear differences in the proportion of trait states. Urbanized grid-cells had e.g., higher proportions of wind-pollinated plants, plants with scleromorphic leaves or plants dispersed by animals, and lower proportions of insect-pollinated plants, plants with hygromorphic leaves or plants dispersed by wind than other grid-cells. Our study shows that shifts in land use can change the trait state composition of plant assemblages. Far-reaching urbanization might consequently homogenize our flora with respect to trait state frequency.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/

28549. Urbanization effects on carabid diversity in boreal forests

Creator:
Venn, Stephen J., Kotze, D. Johan, and Niemelä, Jari
Type:
article, model:article, and TEXT
Subject:
Boreal forest, carabid beetles, urbanization, urban forests, and urban green space and urban-rural gradient
Language:
English
Description:
Carabid abundance, species richness and diversity were compared along an urban-rural gradient in Helsinki, Finland. Increased urbanization was found to result in significant reductions in species richness, though the reductions in abundance and diversity were not statistically significant. Forest habitat-specialist species were scarce in rural sites and virtually absent from urban and suburban sites. There was no evidence of higher diversity at intermediate disturbance levels (suburban sites), as predicted by the intermediate disturbance hypothesis. Species with flight ability and the ability to utilize open habitat were more predominant in urban and suburban sites. Flightless species were more predominant in rural and suburban sites. Carabid abundance data were sufficient to reveal the negative impact of urbanization, so similar studies could be conducted in regions where carabid taxonomy is poorly known. Species composition patterns do, however, provide invaluable information. To conclude, if biodiversity is to be maintained in urban areas, priority must be given to the provision of those habitat features which are essential for sensitive species, such as decaying wood and wet microhabitats. These must be incorporated into urban green networks in particular, if biodiversity and species other than common generalists are to benefit from them.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

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