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6847. Earliest pottery in Eurasia continent

Creator:
Pavlů, Ivan, Machová, Tereza, and Pchálková, Alžběta
Format:
bez média and svazek
Type:
model:article and TEXT
Subject:
Neolithic, Mesoneolithic, Palaeoneolithic, Pleistocene, Holocene, Siberia, Eurasia, neolit, mesoneolit, paleoneolit, pleistocén, holocén, Sibiř, and Eurasie
Language:
Czech
Description:
This paper presents an overview of the latest information about the beginnings of the technology of pottery making in the area of the forest-steppe belt in Siberia and the Russian part of Eastern Europe all the way to the Ural Mountains. From a continental point of view, a brief spatiotemporal diagram presents a completely different background of the beginnings of pottery in our lands and also in corresponding parts of Southeast Europe, where the origin of pottery has traditionally been linked to the Neolithisation of Europe. The earliest pottery technology in China dates back to 20 000 BP, followed by all the subsequent data from the Far East area to Lake Baikal. The earliest pottery culture, Jomon, which had been developing in Japan for more than ten thousand years, is not included here. In the Russian part of Eastern Europe, pottery technology starts developing only after 8 000 BP. Typologically uniform and mostly unchangeable development of beaker-shaped pottery, mostly with a pointed bottom, is common for both these areas. This development continues in Scandinavia and adjacent areas of the Baltic and in Atlantic Europe. In the central parts of Europe, similar shapes only occur sporadically in the earliest period. However, the earliest Eurasian pottery had influenced the development of later prehistoric periods. Numerous settlement groups on the Eurasian continents were characterised by two traditions that are archaeologically recognisable. In simple terms, one of the traditions was agricultural, the other conservative. and Práce předkládá přehled nejnovějších informací o počátcích technologie výroby keramiky v oblastech lesostepního pásma Sibiře a ruské východní Evropy až k Uralu. Data nejstarší keramické technologie v Číně přesahují číslo 20 tis. BC. Na území ruské východní Evropy začíná vývoj keramické technologie většinou až po roce 8000 BC. Obě oblasti spojuje typologicky jednotný a málo proměnlivý vývoj kotlovitých tvarů převážně se špičatým dnem. Na tento vývoj navazuje srovnatelně kulturní posloupnost ve Skandinávii a v přilehlých oblastech Baltu i Evropského pobřeží Atlantiku. V centrálních oblastech Evropy se podobné tvary vyskytnou v nejstarším období zcela ojediněle. Eurasijská nejstarší keramika však nepochybně ovlivnila vývoj i v pozdějších pravěkých obdobích. Početné skupiny osídlení na evropském i eurasijském kontinentu se vyznačovaly dvojí tradicí hmatatelnou archeologicky nejen v keramice. Zjednodušeně řečeno, jedna byla zemědělská, druhá konzervativní.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

6848. Early and late effects of hyperbaric oxygen treatment on oxidative stress parameters in diabetic patients

Creator:
Gürdöl, Figen, Cimşit, M., Öner-İyidoğan, Y., Körpinar, Ş., Yalçinkaya, S., and Koçak, H.
Format:
print, bez média, and svazek
Type:
article, články, model:article, and TEXT
Subject:
Biochemie. Molekulární biologie. Biofyzika, biochemie, hyperbarická oxygenoterapie, diabetická noha, biochemistry, hyperbaric medicine, diabetic foot, isoprostanes, malondialdehyde, advanced oxidation protein products, 2, and 577
Language:
English
Description:
Exposure to hyperbaric oxygen leads to increased amount of reactive oxygen species (ROS) that are derived from various sources. After the discovery that ROS can function as signaling molecules, the idea of ROS being hazardous to biological tissues has been challenged. The aim of this study was to examine the changes in oxidative stress parameters in diabetics undergoing hyperbaric oxygen therapy (HBOT) due to foot ulcers. Twenty patients, who received HBOT for diabetic foot ulcers, were included in the study. Blood samples were taken before HBOT and 30 min after exit from the chamber, on the day of the first and the 15th HBOT sessions. They were used for the determinations of malondialdehyde (MDA), 8-isoprostane and advanced oxidation protein products (AOPPs). 8-Isoprostane and AOPP levels were not altered significantly after the first HBOT session, while both were increased on the fifteenth day (p<0.05). MDA was significantly increased only after the first HBOT session, and remained unchanged on the fifteenth day (within-day variations). Plasma AOPP levels were lowered significantly after fifteen consecutive HBOT sessions (between-day variations). Decreased AOPP levels suggest that increased oxygenation of tissues due to HBO therapy may activate some endogenous factors that prevent hazardous effects of the disease itself., F. Gürdöl, M. Cimşit, Y. Öner-İyidoğan, Ş. Körpinar, S. Yalçinkaya, H. Koçak., and Obsahuje bibliografii a bibliografické odkazy
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

6849. Early changes during skin repair using tissue-engineered dermal template in a full-thickness burn

Creator:
Gál, P., Fröhlichová, L., Čoma, M., Pafčuga, I., Šuca, H., Grossová, I., Hríbiková, Z., Sticová, E., and Zajíček, R.
Format:
bez média and svazek
Type:
model:article and TEXT
Subject:
wound healing, angiogenesis, artificial skin, tissue engineering, and burn injury
Language:
English
Description:
Rapid wound closure in extensively burned patients has remained one of the major unresolved issues of medicine. Integra® is the most widely established artificial skin, which is composed of a porous matrix of cross-linked bovine collagen and chondroitin 6-sulphate covered by a semi-permeable silicone layer. We present here a (immuno)histological study of a severely burned patient with a full-thickness burn treated with a tissue-engineered dermal template (Integra®) and split-thickness skin graft-based protocol. Immunohistochemical investigation of the artificial dermis revealed that immune cell infiltration reached its peak on day 10. Tissue immunophenotyping found an increase in CD3+ cells over the course of the study as well as CD4 and CD8 positivity on day 40, indicating remaining T-cell subpopulations. We observed weak/no infiltration of NK cells (CD56+). In conclusion, the use of bi-layer Integra® represents a feasible and safe procedure resulting in formation of non-irritating dermal substitutes.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

6850. Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle pattern versus troponin T determination

Creator:
Martin Štěrba, Tomáš Šimůnek, Popelová, O., Anna Potáčová, Michaela Adamcová, Yvona Mazurová, Magdalena Holečková, and Vladimír Geršl
Format:
print, bez média, and svazek
Type:
article, články, model:article, and TEXT
Subject:
Biochemie. Molekulární biologie. Biofyzika, fyziologie, kardiotoxicita, troponiny, physiology, cardiac toxicity, troponins, daunorubicin, anthracyclines, early detection, diastolic dysfunction, cardiac troponin T, 2, and 577
Language:
English
Description:
Anthracycline cardiotoxicity represents a serious risk of anticancer chemotherapy. The aim of the present pilot study was to compare the potential of both the left ventricular (LV) filling pattern evaluation and cardiac troponin T (cTnT) plasma levels determination for the early detection of daunorubicin-induced cardiotoxicity in rabbits. The echocardiographic measurements of transmitral LV inflow as well as cTnT determinations were performed weekly for 10 weeks in daunorubicin (3 mg/kg weekly) and control groups (n=5, each). Surprisingly, no significant changes in LV-filling pattern were observed through the study, most likely due to the xylazine-containing anesthesia, necessary for appropriate resolving of the E and A waves. In contrast to the echographic measurement, the dP/dt min index obtained invasively at the end of the study revealed a significant im pairment in LV relaxation, which was further supported by observed disturbances in myocardial collagen content and calcium homeostasis. However, at the same time cTnT plasma levels were progressively rising in the daunorubicin-treated animals from the 5th week (0.024±0.008 μg/l) until the end of the experiment (0.186±0.055 μg/l). Therefore, in contrast to complicated non-invasive evaluation of diastolic function, cTnT is shown to be an early and sensitive marker of anthracycline-induced cardiotoxicity in the rabbit model., M. Štěrba, T. Šimůnek, O. Popelová, A. Potáčová, M. Adamcová, Y. Mazurová, M. Holečková, V. Geršl., and Obsahuje bibliografii a bibliografické odkazy
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

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