Isolation and characterisation of Plasmodium falciparum (Welch, 1897) soluble antigens from infected patient plasma, Western blotting, thermal stability and ELISA assays using hyperimmune IgG-antimalaria antibodies was the main objective of this work. A circulating antigen of approximately Mr 33-35 kDa with good specificity and antigenicity, in the plasma of malarial patients was shown. Heating at 100°C did not destroy its antigenicity. When fractions highly enriched in the 33-35 kDa proteins were used in ELISAs, a seroreactivity in plasma obtained from primary-infected individuals was found. Controls from normal patients were always negative. The antigenic characteristics suggest that it may be included within the group of new described Plasmodium soluble antigens.
Elevated levels of eukaryotic initiation factor 4E (eIF4E) are implicated in neoplasia, with cumulative evidence pointing to its role in the etiopathogenesis of hematological diseases. As a node of convergence for several oncogenic signaling pathways, eIF4E has attracted a great deal of interest from biologists and clinicians whose efforts have been targeting this translation factor and its biological circuits in the battle against leukemia. The role of eIF4E in myeloid leukemia has been ascertained and drugs targeting its functions have found their place in clinical trials. Little is known, however, about the pertinence of eIF4E to the biology of lymphocytic leukemia and a paucity of literature is available in this regard that prospectively evaluates the topic to guide practice in hematological cancer. A comprehensive analysis on the significance of eIF4E translation factor in the clinical picture of leukemia arises, therefore, as a compelling need. This review presents aspects of eIF4E involvement in the realm of the lymphoblastic leukemia status; translational control of immunological function via eIF4E and the state-of-the-art in drugs will also be outlined., V. Venturi, T. Masek, M. Pospisek., and Obsahuje bibliografii
Small bowel obstruction is a common clinical problem presenting with abdominal distention, colicky pain, absolute constipation and bilious vomiting. There are numerous causes, most commonly attributed to an incarcerated hernia, adhesions or obstructing mass secondary to malignancy. Here we present an unusual cause of a small bowel obstruction secondary to an incarcerated incisional hernia in association with an acute organoaxial gastric volvulus. and N. R. Kosai, H. S. Gendeh, M. Noorharisman, P. A. Sutton, S. Das
Twenty eight species of winter-active Heleomyzidae were collected during a long-term study in Poland. More than 130 samples of insects, including Heleomyzidae, were collected from the surface of snow in lowland and mountain areas using a semi-quantitative method. Lowland and mountain assemblages of Heleomyzidae recorded on snow were quite different. Heleomyza modesta (Meigen, 1835) and Scoliocentra (Leriola) brachypterna (Loew, 1873) dominated in the mountains, Tephrochlamys rufiventris (Meigen, 1830) mainly in the lowlands and Heteromyza rotundicornis (Zetterstedt, 1846) was common in both habitats. Heleomyzidae were found on snow during the whole period of snow cover, but the catches peaked from late November to the beginning of February. In late winter and early spring the occurrence of heleomyzids on snow decreased. Most individuals were active on snow at air temperatures between -2 and +2.5°C. A checklist of 78 winter active European Heleomyzidae is presented. Helomyza nivalis Wahlgren, 1918 is herein considered as a new junior synonym of Helomyza caesia Meigen, 1830, syn. n., Agnieszka Soszyńska-Maj, Andrzej J. Woźnica., and Obsahuje bibliografii
Using a distributional approach to integration in superspace, we investigate a Cauchy-Pompeiu integral formula in super Dunkl-Clifford analysis and several related results, such as Stokes formula, Morera's theorem and Painlevé theorem for super Dunkl-monogenic functions. These results are nice generalizations of well-known facts in complex analysis., Hongfen Yuan., and Obsahuje bibliografické odkazy
In the class of real hypersurfaces M²n−¹ isometrically immersed into a nonflat complex space form Mn(c) of constant holomorphic sectional curvature c (≠ 0) which is either a complex projective space ℂPn(c) or a complex hyperbolic space ℂHn(c) according as c > 0 or c < 0, there are two typical examples. One is the class of all real hypersurfaces of type (A) and the other is the class of all ruled real hypersurfaces. Note that the former example are Hopf manifolds and the latter are non-Hopf manifolds. In this paper, inspired by a simple characterization of all ruled real hypersurfaces in Mn(c), we consider a certain real hypersurface of type (A2) in ℂPn(c) and give a geometric characterization of this Hopf manifold., Byung Hak Kim, In-Bae Kim, Sadahiro Maeda., and Obsahuje bibliografii
If (M,∇) is a manifold with a symmetric linear connection, then T*M can be endowed with the natural Riemann extension g¯ (O. Kowalski and M. Sekizawa (2011), M. Sekizawa (1987)). Here we continue to study the harmonicity with respect to g¯g¯ initiated by C. L.Bejan and O.Kowalski (2015). More precisely, we first construct a canonical almost para-complex structure PP on (T*M, g¯) and prove that P is harmonic (in the sense of E.Garciá-Río, L.Vanhecke and M. E.Vázquez-Abal (1997)) if and only if g¯ reduces to the classical Riemann extension introduced by E.M. Patterson and A.G. Walker (1952)., Cornelia-Livia Bejan, Şemsi Eken., and Obsahuje bibliografii
Numerous coccidian stages were found in the kidney tubules of the golden carp (Carassius auratus gibelio). The merogonial and gamogonial stages were localized extracytoplasmally in the microvillous region of the epithelial cells. The host-parasite interface consisted of i) a large area where the parasite was separated from the host cytoplasm by the parasitophorous vacuole membrane only, and ii) a zone of multiple fusions of the host cell membrane investing the parasite to the neighbouring microvilli. The taxonomic status of the extracytoplasmic stages is not clear, however, their possible appurtenance to Eimeria scardimi, which was frequently found in the kidneys of golden carps in the same population, is discussed.
For n=2m\geqslant 4, let \Omega\in \mathbb{R}^{n} be a bounded smooth domain and N\subset \mathbb{R}^{L} a compact smooth Riemannian manifold without boundary. Suppose that \left \{ uk \right \}\in W^{m,2}\left ( \Omega ,N \right ) is a sequence of weak solutions in the critical dimension to the perturbed m-polyharmonic maps \frac{{\text{d}}}{{{\text{dt}}}}\left| {_{t = 0}{E_m}({\text{II}}(u + t\xi )) = 0} \right with Ωk → 0 in W^{m,2}\left( \Omega ,N \right )* and {u_k} \rightharpoonup u weakly in W^{m,2}\left( \Omega ,N \right ). Then u is an m-polyharmonic map. In particular, the space of m-polyharmonic maps is sequentially compact for the weak- W^{m,2} topology., Shenzhou Zheng., and Obsahuje seznam literatury