A large outbreak of haemolytic uraemic syndrome and bloody diarrhoea caused by the pathogenic E. coli strain in Germany in 2011 has increased attention to foodborne diseases – bacterial infections linked to the consumption of fresh produce. Since the early 1990s, evidence is emerging that en - teropathogenic bacteria have the ability to grow and persist on crop plants for prolonged periods of time, including until harvest, and to be the carrier of illness. and Václav Kůdela.
V již tradičním příspěvku věnovanému úlohám z fyzikálních olympiád se tentokrát zaměřujeme na předbohrovské modely atomu. První úloha je zaměřena na Thomsonův "pudinkový" model atomu a druhá pojednává o Rutherfordově planetárním modelu., Martin Kapoun, Jan Kříž, Ivo Volf, Bohumil Vybíral., and Obsahuje seznam literatury
Recently, more and more efforts are directed towards developing new imaging and drug-delivery options based on various nanoparticles, exploiting their unique properties. Here, ultra-small gold nanoparticles functionalized with widely used polyethylene glycol and its amine-terminated form were tested in respect of their potential interactions with human immune cells (cell line and primary cells). The results showed that differently terminated ultrasmall gold nanoparticles represent an interesting theranostic platform as they are harmless to immune cells (not inducing cytotoxicity and severe immune response) and on the other hand, they can serve as imaging and/or drug delivery agents using e.g. monocytes/ macrophages as “Trojan horses” to deliver these nanoparticles across the blood-brain barrier and diagnose or treat pathologies of the central nervous system.