Lyme borreliosis: insights into tick- / host-borrelia relations

Title:

Lyme borreliosis: insights into tick- / host-borrelia relations

Creator:

Grubhoffer, Libor, Golovchenko, Maryna, Vancová, Marie, Zacharovová-Slavíčková, Klára, Rudenko, Nataliia, and Oliver Jr., James H.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:2c36ab7c-a8da-44b7-86f4-30a89899c1d5
uuid:2c36ab7c-a8da-44b7-86f4-30a89899c1d5
doi:10.14411/fp.2005.039

Subject:

borrelia spirochete, Lyme borreliosis, ticks, vectors, interactions, and glycoproteins

Type:

model:article and TEXT

Format:

bez média and svazek

Description:

Lyme borreliosis (LB) is a serious infectious disease of humans and some domestic animals in temperate regions of the Northern Hemisphere. It is caused by certain spirochetes in the Borrelia burgdorferi sensu lato (s.l.) species complex. The complex consists of 11 species (genospecies). Borrelia burgdorferi sensu stricto (s.s.), Borrelia garinii and Borrelia afzelii are the major agents of human disease. Borrelia burgdorferi s.l. species are transmitted mainly by ticks belonging to the Ixodes ricinus species complex plus a few additional species not currently assigned to the complex. B. burgdorferi infections may produce an acute or chronic disease with a wide array of clinical symptoms such as erythema migrans (EM), carditis, arthritis, neuroborreliosis, and acrodermatitis chronica atrophicans (ACA). Differences in LB spirochetes ''genospecies'' and strains/isolates determine the occurrence and severity of this multi-system disease. Accurate and reliable identification of the LB spirochetes in ticks as well as knowledge of their prevalence are essential for prevention against the disease and development of an effective vaccine. An overview of the knowledge of molecular factors with emphasis on potential protein-carbohydrate interactions in the tick-borrelia system is the main focus of this review.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Coverage:

279-294

Source:

Folia parasitologica | 2005 Volume:52 | Number:4

Harvested from:

CDK

Metadata only:

false