Experimental microsporidiosis in immunocompetent immunodeficient mice and monkeys

Title:

Experimental microsporidiosis in immunocompetent immunodeficient mice and monkeys

Creator:

Didier, E.S., Varner, P.W., Didier, P.J., Aldras, A.M., Millichamp, N.J., Murphey-Corb, M., Bohm, R., and Shadduck, J.A.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:796fb99b-286f-4280-a173-45243b252f51
uuid:796fb99b-286f-4280-a173-45243b252f51
urnnbn:urn:nbn:cz:aba007-000dh4

Subject:

Microsporidia, AIDS, opportunistic infection, Nosema, Encephalitozoon, encephaiitozoonosis, and microsporidiosis

Type:

model:internalpart and TEXT

Format:

print

Description:

Microsporidia cause opportunistic infections in AIDS patients and commonly infect laboratory animals, as well. Euthymie C57B1/6 mice experimentally infected with intraperitoneal injections of lxlO6 Encephalitozoon cuniculi Levaditi, Nicolau et Schoen, 1923, Encephalitozoon hellem Didier et al., 1991, or Nosema comeum Shadduck et al., 1990 displayed no clinical signs of disease. Athymic mice, however, developed ascites and died 8-16 days after inoculation with N. comeum, 21-25 days after inoculation with E. cuniculi, and 34-37 days after inoculation with E. hellem. All athymic mice displayed hepatomegaly, dilated intestine and accumulation of ascites fluid. Granulomatous lesions were primarily located in the liver, lung, pancreas, spleen, and on serosal surfaces of abdominal organs.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Coverage:

1-11 and 3-13

Source:

Folia parasitologica | 1994 Volume:41 | Number:1

Harvested from:

CDK

Metadata only:

false