The steroid spectrum during and after quitting smoking

Title:

The steroid spectrum during and after quitting smoking

Creator:

Jandikova, H., Michaela Dušková, Kateřina Šimůnková, Racz, B., Hill, M., Eva Králíková, Karel Vondra, and Luboslav Stárka

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:93441b2f-5b7f-4f36-990f-e1f92fb8e7ca
uuid:93441b2f-5b7f-4f36-990f-e1f92fb8e7ca
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, muži, odvykání kouření, predikce, testosteron, men, smoking cessation, prediction, testosterone, SHBG, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Addiction to tobacco results in an imbalance of endocrine homeostasis in both sexes. This can also have impacts on fertility problems. The male reproductive system is less susceptible than that of females, with a worsening spermiogram in smokers, the most cited effect in the literature. However, the literature is inconsistent as to the effects of smoking on steroid hormone levels in men, and there is very little data on the effects of quitting smoking in men. In this study we followed 76 men before quitting smoking, and then after 6, 12, and 24 weeks and 1 year of abstinence. We measured basic anthropomorphic data and steroid hormone levels along with steroid neuroactive metabolites using GC-MS. We demonstrate lower androgen levels in men who smoke, and these changes worsened after quitting smoking. There was a drop in SHBG already in the first week of non-smoking, and levels continued to remain low. Male smokers have lower androgen levels compared to non-smokers. The lower the initial level of androgen, the lower the likelihood of success in quitting smoking. Changes in steroid hormones proved to be a promising marker for the prediction of success in quitting smoking., H. Jandikova, M. Duskova, K. Simunkova, B. Racz, M. Hill, E. Kralikova, K. Vondra, L. Starka., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2015 Volume:64 | Number:Suppl 2

Harvested from:

CDK

Metadata only:

false