In vivo, in vitro and pharmacologic models of Parkinson's disease

Title:

In vivo, in vitro and pharmacologic models of Parkinson's disease

Creator:

Salari, S. and Bagheri, M.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:bce08a2d-1e31-4c6d-8102-df36bc9db424
uuid:bce08a2d-1e31-4c6d-8102-df36bc9db424
doi:10.33549/physiolres.933895

Subject:

Parkinson’s disease and in vivo/vitro models

Type:

model:article and TEXT

Format:

bez média and svazek

Description:

Parkinson's disease (PD), which is the second most common neurodegenerative disorder after Alzheimer's disease, is firstly defined after James Parkinson's report. It carries motor symptoms such as resting tremor, bradykinesia and rigidity of skeletal muscle and freezing of gait. Furthermore, non-motor symptoms such as cognitive and behavioral problems, besides sensory impairments are seen in the patients. However, they may also suffer from sleep disorders or autonomic dysfunction. Although there are some medications in order to symptomatic management, but unfortunately, scientist could not have found exact approaches to cure this disease. Hence, producing a model which can express the most pathophysiologic and behavioral aspects of the disease is a desire. In this paper, we aimed to describe the different models of Parkinson's disease in brief.

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2019 Volume:68 | Number:1

Harvested from:

CDK

Metadata only:

false