Effect of terguride on insulin binding, insulinaemia, glucose tolerance and hyperlipaemia in lean SHR Koletsky rats

Title:

Effect of terguride on insulin binding, insulinaemia, glucose tolerance and hyperlipaemia in lean SHR Koletsky rats

Creator:

Golda, V. and Hilgertová, J.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:d01eb359-6af8-4b94-abaa-21976aa9ea3a
uuid:d01eb359-6af8-4b94-abaa-21976aa9ea3a

Subject:

glucose tolerance, insulin binding, insulinaemia, fat pads, plasma cholesterol, plasma triglycerides, and terguride

Type:

article, model:article, and TEXT

Description:

Glucose tolerance, insulin binding to erythrocytes, insulinaemia, plasma total cholesterol, plasma triglycerides, weight of fat pads, food consumption and body weight changes were studied in genetically hypertensive lean Koletsky rats. Long-term treatment with dopaminergic agonist terguride (0.2 mg/kg/day) normalized glucose tolerance and increased the percentage of bound insulin to erythrocytes in both sexes. Terguride decreased insulinaemia, cholesterolaemia, fat pads and body weight only in female rats. Food consumption was not influenced by terguride over the injection period.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 1997 Volume:46 | Number:6

Harvested from:

CDK

Metadata only:

false