Effects of cyclic stretching exercise on long-lasting hyperalgesia, joint contracture, and muscle injury following cast immobilization in rats

Title:

Effects of cyclic stretching exercise on long-lasting hyperalgesia, joint contracture, and muscle injury following cast immobilization in rats

Creator:

Hayashi, Kazuhiro, Fukuyasu-Matsuo, Saori, Inoue, Takayuki, Fujiwara, Mitsuhiro, Asai, Yuji, Iwata, Masahiro, and Suzuki, Shigeyuki

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:d16808c7-95cf-465b-9af7-c3c9cbb46ee7
uuid:d16808c7-95cf-465b-9af7-c3c9cbb46ee7
issn:0862-8408
doi:10.33549/physiolres.934437

Subject:

strečink, fyziologie, stretching exercises, physiology, hyperalgesia, muscle damage, immobilization, 14, and 612

Type:

model:article and TEXT

Format:

počítač and online zdroj

Description:

The effects of exercise on mechanical hyperalgesia, joint contracture, and muscle injury resulting from immobilization are not completely understood. This study aimed to investigate the effects of cyclic stretching on these parameters in a rat model of chronic post-cast pain (CPCP). Seventeen 8-week-old Wistar rats were randomly assigned to (1) control group, (2) immobilization (CPCP) group, or (3) immobilization and stretching exercise (CPCP+STR) group. In the CPCP and CPCP+STR groups, both hindlimbs of each rat were immobilized in full plantar flexion with a plaster cast for a 4-week period. In the CPCP+STR group, cyclic stretching exercise was performed 6 days/week for 2 weeks, beginning immediately after cast removal prior to reloading. Although mechanical hyperalgesia in the plantar skin and calf muscle, ankle joint contracture, and gastrocnemius muscle injury were observed in both immobilized groups, these changes were significantly less severe in the CPCP+STR group than in the CPCP group. These results clearly demonstrate the beneficial effect of cyclic stretching exercises on widespread mechanical hyperalgesia, joint contracture, and muscle injury in a rat model of CPCP., Kazuhiro Hayashi, Saori Fukuyasu-Matsuo, Takayuki Inoue, Mitsuhiro Fujiwara, Yuji Asai, Masahiro Iwata, Shigeyuki Suzuki., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Coverage:

861-870

Source:

Physiological research | 2020 Volume:69 | Number:5

Harvested from:

CDK

Metadata only:

false