In this paper, we employ some new techniques to study the existence of positive periodic solution of $n$-species neutral delay system
\[ N^{\prime }_i(t)=N_i(t)\biggl [a_i(t)-\sum _{j=1}^n\beta _{ij}(t)N_j(t)- \sum _{j=1}^nb_{ij}(t)N_j(t-\tau _{ij}(t))-\sum _{j=1}^nc_{ij}(t) N^{\prime }_j(t-\tau _{ij}(t))\biggr ]. \] As a corollary, we answer an open problem proposed by Y. Kuang.