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1. Lack of an association between apolipoprotein B Xbal polymorphism and blood lipid parameters in childhood

Creator:
Hubáček, J. A., Pistulková, H., Píša, Z., Valenta, Z., Škodová, Z., and Poledne, R.
Type:
article, model:article, and TEXT
Subject:
apolipoprotein B, children, gene polymorphism, hypercholesterolaemia, and Xbal
Language:
English
Description:
The frequencies of the alleles of Xbal polymorphism in the apolipoprotein B gene were determined in two groups of children, 82 with high (HCG) and 86 with low (LCG) cholesterol levels. A slightly higher incidence of the X2X2 genotype in HCG was found, but the differences were not statistically significant. No relations were found between the Xbal polymorphic site and the levels of serum lipids and lipoproteins. Common Xbal polymorphism in the apolipoprotein B gene does not determine significantly the plasma cholesterol levels in childhood.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public