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Start Over Creator Pajovic, S. B.

1. Glutathione-dependent antioxidant enzyme activities and glutathione content in the rat brain at different stages of oestrous cycle

Creator:
Saičic, Z. S., Pajovic, S. B., Korac, B., Spasic, M. B., Martinovic, J. V., and Petrovic, V. M.
Type:
article, model:article, and TEXT
Subject:
brain, oestrous cycle, glutathione, glutathione-dependent enzymes, and rats
Language:
English
Description:
Enzymatic activities of glutathione peroxidase, glutathione-S-transferase, glutathione reductase and catalase, as we 11 as the glutathione content were measured in the brain tissue of regularly cycling rats at dioestrus, proestrus an*d estrus. The activity of glutathione peroxidase was found to be suppressed at proestrus, whereas that of catalase was increased at dioestrus. Glutathione transferase and glutathione reductase activities, as well as the glutathione comtent appeared to be stable during the oestrous cycle. These results suggest that, in the female rat, glutathione peroxidase and catalase activities in the brain tissue are influenced by the ovarian hormone status.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

2. Superoxide dismutase activities in different tissues of female rats treated with olive oil

Creator:
Pajovic, S. B., Kasapovic, J., and Martinovic, J.
Type:
article, model:article, and TEXT
Subject:
superoxide dismutase, olive oil, brain, thymus, and liver
Language:
English
Description:
The activities of cytosol superoxide dismutase (CuZnSOD) and mitochondrial superoxide dismutase (MnSOD) were measured in subcellular fractions of homogenates prepared from the brain, thymus and liver of ovariectomized (OVX) female rats, non-treated or treated 24 h prior to sacrifice with a single s.c. dose of 0.1 ml olive oil. In the brain, neither MnSOD nor CuZnSOD were affected by olive oil, whereas in the thymus the olive oil injection elevated CuZnSOD and did not affect MnSOD activity. At the same time, the activity of CuZnSOD was reduced and that of MnSOD was elevated in the liver following oil treatment. These results suggest that olive oil has modulatory effects on the expression of CuZnSOD and MnSOD activity in the liver and of CuZnSOD in the thymus of female rats.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public