Search

Start Over Creator Peng, Z.

1. Gastrodin ameliorates anxiety-like behaviors and inhibits IL-1β level and p38 MAPK phosphorylation of hippocampus in the rat model of posttraumatic stress disorder

Creator:
Peng, Z., Huan Wang, Zhang, R., Chen, Y., Xue, F., Nie, H., Wu, D., Wang, Y., Wang, H., and Tan, Q.
Format:
print
Type:
article, články, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, úzkost, stres (fyziologie), PTSD, gastrodin, IL-6, IL-1β, iNOS, p38, 14, and 612
Language:
English
Description:
Z. Peng ... [et. al.]. and Obsahuje bibliografii
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

2. Multi-Step Hybrid Prediction Model of Baltic Supermax Index Based on Support Vector Machine

Creator:
Guan , F., Peng, Z., Wang, K., Song, X., and Gao, J.
Format:
bez média and svazek
Type:
model:article and TEXT
Subject:
BSI prediction, Support Vector Machine (SVM), multi-step, and hybrid
Language:
English
Description:
Accurate prediction of the Baltic index makes great difference to the strategic decision and risk avoidance of the enterprise. For the multi-step Baltic Supermax Index prediction, direct prediction and iterative prediction has its own advantages. Therefore, in this paper, in combination with direct and iterative prediction, based on Support Vector Machine (SVM), a hybrid multistep prediction model is put forward. In hybrid model, the output from the iterative model is a rough prediction and it need also be adjusted based on the output from the direct model. And weekly BSI data from January 2011 to November 2014 are used to test the model. The results show that the hybrid multistep prediction model based on SVM has high accuracy, and is feasible in the BSI prediction.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

3. Sirt1 mediates improvement in cognitive defects induced by focal cerebral ischemia following hyperbaric oxygen preconditioning in rats

Creator:
Ding, P., Ren, P., He, S., He, M., Zhang, G., Chen, Y., Sang, H., Peng, Z., and Yan, W.
Type:
article, model:article, and TEXT
Subject:
HBO-PC, Sirt1, MCAO, and cognitive defects
Language:
English
Description:
Hyperbaric oxygen preconditioning (HBO-PC) has been proposed as a safe and practical approach for neuroprotection in ischemic stroke. However, it is not known whether HPO-PC can improve cognitive deficits induced by cerebral ischemia, and the mechanistic basis for any beneficial effects remains unclear. We addressed this in the present study using rats subjected to middle cerebral artery occlusion (MCAO) as an ischemic stroke model following HBO-PC. Cognitive function and expression of phosphorylated neurofilament heavy polypeptide (pNF-H) and doublecortin (DCX) in the hippocampus were evaluated 14 days after reperfusion and after short interfering RNA-mediated knockdown of sirtuin1 (Sirt1 ). HBO-PC increased pNF-H and DCX expression and mitigated cognitive deficits in MCAO rats. However, these effects were abolished by Sirt1 knockdown. Our results suggest that HBO-PC can protect the brain from injury caused by ischemia-reperfusion and that Sirt1 is a potential molecular target for therapeutic approaches designed to minimize cognitive deficits caused by cerebral ischemia.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public