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Start Over Creator Růžička, Jiří Date Unknown

2. Člověk a (jeho) práce

Creator:
Růžička, Jiří
Type:
article, model:article, and TEXT
Language:
Czech
Description:
The article offers a comparison of two near-contemporary views of Karl Marx in the history of thought those of Louis Althusser in the book Reading Capital and of Michel Foucault in the book The Order of Things. The tertium comparationis is provided by Marx’s conception of man and work. Despite their common starting points (a critique of dialectics and humanism), the two authors bring diametrically opposed interpretations to Marx. The article argues that the most significant difference is one of methodology. While Althusser takes as his starting point a conception of the history of science due to G. Bachelard, Foucault constructs his own history of knowledge which, thanks to the thesis of the discontinuity between particular periods, constitutes a radicalisation of the Bachelard-Althusser approach. On the other hand a critical eye is, however, cast on Foucault’s overly selective reading of Marx. The article also indicates the prospects for a synthesis of Althusser’s symptomatic history and Foucault’s archeology.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

5. Hyperbaric oxygen enhances collagen III formation in wound of ZDF rat

Creator:
Růžička, Jiří, Grajciarová, Martina, Vištejnová, Lucie, Klein, Pavel, Tichánek, Filip, Tonar, Zbyněk, Dejmek, Jiří, Beneš, Jiří, Bolek, Lukáš, Bajgar, Robert, and Kuncová, Jitka
Format:
počítač and online zdroj
Type:
model:article and TEXT
Subject:
hojení ran, hyperbarická oxygenoterapie, wound healing, hyperbaric oxygen therapy, hyperbaric oxygen, ZDF rat, collagen type, angiogenesis, 14, and 612
Language:
English
Description:
Diabetic foot ulcer (DFU) is a serious complication of diabetes and hyperbaric oxygen therapy (HBOT) is also considered in comprehensive treatment. The evidence supporting the use of HBOT in DFU treatment is controversial. The aim of this work was to introduce a DFU model in ZDF rat by creating a wound on the back of an animal and to investigate the effect of HBOT on the defect by macroscopic evaluation, quantitative histological evaluation of collagen (types I and III), evaluation of angiogenesis and determination of interleukin 6 (IL6) levels in the plasma. The study included 10 rats in the control group (CONT) and 10 in the HBOT group, who underwent HBOT in standard clinical regimen. Histological evaluation was performed on the 18th day after induction of defect. The results show that HBOT did not affect the macroscopic size of the defect nor IL6 plasma levels. A volume fraction of type I collagen was slightly increased by HBOT without reaching statistical significance (1.35±0.49 and 1.94±0.67 %, CONT and HBOT, respectively). In contrast, the collagen type III volume fraction was ~120 % higher in HBOT wounds (1.41±0.81 %) than in CONT ones (0.63±0.37 %; p=0.046). In addition, the ratio of the volume fraction of both collagens in the wound ((I+III)w) to the volume fraction of both collagens in the adjacent healthy skin ((I+III)h) was ~65 % higher in rats subjected to HBOT (8.9±3.07 vs. 5.38±1.86 %, HBOT and CONT, respectively; p=0.028). Vessels density (number per 1 mm2 ) was found to be higher in CONT vs. HBOT (206.5±41.8 and 124±28.2, respectively, p<0.001). Our study suggests that HBOT promotes collagen III formation and decreases the number of newly formed vessels at the early phases of healing., Jiří Růžička, Martina Grajciarová, Lucie Vištejnová, Pavel Klein, Filip Tichánek, Zbyněk Tonar, Jiří Dejmek, Jiří Beneš, Lukáš Bolek, Robert Bajgar, Jitka Kuncová., and Obsahuje bibliografii
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

6. Hyperbaric oxygen influences chronic wound healing - a cellular level review

Creator:
Růžička, Jiří, Dejmek, Jiří, Bolek, Lukáš, Beneš, Jiří, and Kuncová, Jitka
Format:
počítač and online zdroj
Type:
model:article and TEXT
Subject:
hyperbaric oxygen, wound healing, reactive oxygen and nitrogen species, hypoxia inducible factor, and heat shock protein
Language:
English
Description:
Chronic wound is a serious medical issue due to its high prevalence and complications; hyperbaric oxygen therapy (HBOT) is also considered in comprehensive treatment. Clinical trials, including large meta-analyses bring inconsistent results about HBOT efficacy. This review is summarizing the possible effect of HBOT on the healing of chronic wound models at the cellular level. HBOT undoubtedly escalates the production of reactive oxygen and nitrogen radicals (ROS and RNS), which underlie both the therapeutic and toxic effects of HBOT on certain tissues. HBOT paradoxically elevates the concentration of Hypoxia inducible factor (HIF) 1 by diverting the HIF-1 degradation to pathways that are independent of the oxygen concentration. Elevated HIF-1 stimulates the production of different growth factors, boosting the healing process. HBOT supports synthesis of Heat shock proteins (HSP), which are serving as chaperones of HIF-1. HBOT has antimicrobial effect, increases the effectiveness of some antibiotics, stimulates fibroblasts growth, collagen synthesis and suppresses the activity of proteolytic enzymes like matrix metalloproteinases. All effects of HBOT were investigated on cell cultures and animal models, the limitation of their translation is discussed at the end of this review
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

8. Marxismus jako etika vůle k přetvoření světa. Jaroslav Kabeš a nové cesty marxismu po říjnové revoluci

Creator:
Růžička, Jiří
Format:
bez média and svazek
Type:
model:article and TEXT
Subject:
Jaroslav Kabeš, Marxism, voluntarism, ethics, will, and subjectivity
Language:
Czech
Description:
Text se pokouší sledovat, jakým způsobem se významný český marxista meziválečného období Jaroslav Kabeš snažil rozpracovávat subjektivní stránku marxistické filosofie ve formě specifické etiky. Tuto jeho koncepci autor stati nazval „etikou vůle k přetvoření světa“. Kabešovo úsilí je v textu rámováno „krizí“ marxismu po říjnové revoluci, která vyvolala debatu o dalším směřování marxistické filosofie. Jednou z radikálních odpovědí na tuto situaci byla rehabilitace jejího revolučního charakteru skrze znovuoživení prvků hegelovské dialektiky v Marxových spisech (K. Korsch, G. Lukács). Kabeš se naopak obrátil k tradici voluntaristické filosofie (A. Schopenhauer, F. Nietzsche), ale rovněž k nejranějším Marxovým spisům a Leninově korespondenci, aby zde našel podněty pro svůj projekt materialisticky chápaného etického postoje. and The text attempts to follow the path that Jaroslav Kabeš, a notable Czech Marxist of the interwar period, took to work out the subjective side of Marxist philosophy in the form of a specific ethics. The article’s author calls Kabeš’ conception an “ethics of the will to transform the world.” Kabeš’ efforts are framed in the article by the “crisis” in Marxism that followed the October Revolution and which triggered a debate on the direction that Marxist philosophy should take in the future. One of the radical responses to this situation was to rehabilitate its revolutionary character by reviving the elements of Hegel’s dialectic in Marx’s writings (K. Korsch, G. Lukács). Kabeš, by contrast, turned not only to the philosophical tradition of voluntarism (Schopenhauer, Nietzsche) but also to the earliest writings of Marx and to Lenin’s correspondence so as to find the stimuli for his project of a materialistically understood ethical position.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public